TY  - JOUR
TT  - Plasma Urotensin II Concentration In Gestational Diabetes
AU  - Hursitoglu, Mehmet
AU  - Ekiz, Ali
AU  - Mete, Fatih
AU  - Okuturlar, Yıldız
AU  - Kocoglu, Hakan
AU  - Dumanli, Guleren
AU  - Cakirca, Mustafa
AU  - Anataca, Gulden
AU  - Kuru, Oguzhan
AU  - Dogan, Serkan
AU  - Pehlivan, Bahar
AU  - Tabak, Omur
AU  - Yildirim, Gokhan
AU  - Dogan, Hakan
AU  - Erismis, Betul
PY  - 2017
DA  - December
DO  - 10.25000/acem.336837
JF  - Archives of Clinical and Experimental Medicine
JO  - Arch Clin Exp Med
PB  - Mustafa HASBAHÇECİ
WT  - DergiPark
SN  - 2564-6567
SP  - 66
EP  - 70
VL  - 2
IS  - 3
KW  - ürotensin
KW  - gestasyonel diabet
KW  - gebelik
KW  - glukoz tolerans testi
N2  - Aim: Urotensin II(UII) and its system is implicated in the etiology of many diseases (including diabetesmellitus). We tried in this study to evaluate and compare UII levels ingestational diabetes mellitus (GDM).Methods: Thirty-sixpregnant women (15 non-GDM patients consisted group 1 and 21 GDM patientsconsisted group 2) enrolled in this study. The 3rd group consisted of age matched22 non pregnant healthy women. Plasma UII levels were determined at thebeginning of the study. After 12 weeks of delivery, a second plasma UII was determinedfrom group 1 and 2.Results: GestationalUII levels of both GDM and non-GDM patients were higher than non-pregnanthealthy controls (p=0.0001 for both). Both gestational and postpartum UIIlevels of GDM patients were higher than non-GDM patients but had not reached statisticalsignificance (P≥0.05). Plasma UII concentrations in non-GDM patients significantlydecreased after delivery but not in GDM patients (p=0.036 and p≥0.05,respectively).Conclusion: Thefinding of elevated gestational plasma UII concentrations in GDM patients whichdid not decrease significantly after delivery (in compare to non-GDM patients) showsthat plasma UII levels may have a role in the pathogenesis of GDM. Furtherdetailed studies are needed in this field.
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UR  - https://doi.org/10.25000/acem.336837
L1  - http://dergipark.org.tr/tr/download/article-file/373854
ER  -