TY  - JOUR
TT  - Atresia Ani, Hypospadia and Rudimentary External Genitalia in Two German Holstein Calves
AU  - Usta, Zafer
PY  - 2017
DA  - October
DO  - 10.17094/ataunivbd.347977
JF  - Atatürk Üniversitesi Veteriner Bilimleri Dergisi
PB  - Atatürk Üniversitesi
WT  - DergiPark
SN  - 1306-6137
SP  - 195
EP  - 202
VL  - 12
IS  - 2
KW  - Atreziya ani
KW  - Hypospadia
KW  - Kalıtsal
KW  - Konjenital anomaly
KW  - Rudumenter dış genital organlar
N2  - In the present report, clinical, pathological, and cytogeneticexaminations of a one-day-old male German Holstein calf with atresia ani,hypospadia and rudimentary external genitalia (HYP-AA) and a six-months-oldmale German Holstein calf with hypospadia and rudimentary external genitalia(HYP) are presented. In the first case (HYP-AA), an anal orifice was missing.The urethra opened in the perineum. Consequently, the inguinal region wasinfiltrated with urine. A secondary finding was a vesicle at the anal area witha diameter of approximately 10 cm. Histopathological examination of the analarea of the HYP-AA-calf showed a necrotizing dermatitis with multifocal acutebleedings and diffuse oedema. In addition, an interstitial pneumonia andurethritis were identified. In the clinical examination of the second case(HYP), a penile and preputial aplasia, an incomplete ventral covering by skinand a bifid scrotum were found. Histopathological examination of the HYP-calfrevealed a urethritis with epithelial hyperplasia in the urethra and afollicular hyperplasia of the lymph nodes. The HYP-calf had normally developedtesticles. However, there was no active spermatogenesis. The inbreedingcoefficient for the HYP-AA-calf was 0.684% and for the HYP-calf 5.273% and bothaffected calves had one ancestor in common, a Holstein bull used in artificialinsemination. In conclusion the congenital anomalies of the two cases might bedue to mutations transmitted by the common ancestor.
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UR  - https://doi.org/10.17094/ataunivbd.347977
L1  - https://dergipark.org.tr/tr/download/article-file/356846
ER  -