TY - JOUR TT - Is there a link between lumbar disc herniation and haemogram parameters? AU - Kılınç, Erkan AU - Dağıstan, Yaşar AU - Dağıstan, Emine AU - Coşgun, Zeliha PY - 2018 DA - January Y2 - 2017 DO - 10.21673/anadoluklin.357593 JF - Anatolian Clinic the Journal of Medical Sciences JO - Anatolian Clin PB - Hayat Sağlık ve Sosyal Hizmetler Vakfı WT - DergiPark SN - 2149-5254 SP - 6 EP - 11 VL - 23 IS - 1 KW - ortalama trombosit hacmi KW - kırmızı küre dağılım genişliği KW - inflamasyon KW - lomber disk hernisi N2 - Aim: Inflammatorymechanisms play a key role in the pathogenesis of back pain related to dischernia. Novel and promising inflammatory markers in routine hemogram tests aremean platelet volume (MPV) and red cell distribution width (RDW). We aimed tocompare the MPV and RDW values of lumbar disc herniation (LDH) patients withhealthy subjects and the symptomatic patients with sciatalgia but withoutradiological evidence of lumbar disc herniation.Materialsand Methods: This retrospective cohort study was carried out in thedepartment of neurosurgery of Abant Izzet Baysal University Education andResearch Hospital. We designed three groups including control (n=57), LDH(n=73) and sciatalgia (n=20). Hemogram parameters containing white blood cellcount (WBC), hemoglobin (Hb), hematocrit (Htc), mean corpuscular volume (MCV),RDW, platelet count (PLT), and MPV of the subjects of control, LDH and sciatalgia groups wereevaluated. Results: Mean MPVof the LDH, sciatalgia and control groups were 9.3 ± 1.8 fL, 8.2 ±1.1fL and 8.4±1.0fL, respectively. Mean MPV values of LDHgroup were significantly higher than sciatalgia and control groups(p=0.001).Mean RDW values of the LDH,sciatalgia and control groups were 14.8 ± 1.8, 13.8 ±1.0 and 13.7 ±1.2,respectively. Mean RDW values of LDH group were alsosignificantly higher than sciatalgia and control groups (p=0.001). Discussionand Conclusion: We think that elevated MPV and RDW should be strongindicators of LDH in patients with sciatalgia and they should be consideredprior to imaging studies. However, more prospective studies supporting ourresults are needed. CR - 1. Walker BF. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord. 2000; 13(3): 205-17. 2. Demirdağ F, Ediz L, Özgür A, Tekeoğlu İ. Kronik Lomber Disk Hernili Hastaların Tedavisinde Tens İle Elektroakupunktur Tedavisinin Karşılaştırılması. Van Tıp Dergisi. 2011; 18(1): 15-9. 3. Hoy D, Bain C, Williams G, March L, Brooks P, Blyth F, et al. 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