@article{article_369657, title={Evaluation of left ventricular functions by conventional echocardiography and tissue Doppler imaging in children with rheumatic valve disease}, journal={Çağdaş Tıp Dergisi}, volume={8}, pages={1–6}, year={2018}, DOI={10.16899/gopctd.369657}, author={Yazar, Abdullah and Kararslan, Sevim}, keywords={sol ventrikül fonksiyonları,mitral yetmezlik,doku Doppler görüntüleme}, abstract={<pre style="text-align:justify;line-height:200%;background:#FFFFFF;"> </pre> <p class="MsoNormal" style="line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, ’sans-serif’;color:#000000;">Aim: </span> </b> <b> <span style="font-family:Arial, ’sans-serif’;color:#000000;"> </span> </b> <span lang="en-gb" style="font-size:10pt;line-height:200%;font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">We aimed to evaluate left ventricular functions in children with mitral regurgitation (MR) who were followed up with the diagnosis </span> <span style="font-size:10pt;line-height:200%;font-family:Arial, ’sans-serif’;color:#000000;">rheumatic carditis, by </span> <span lang="en-gb" style="font-size:10pt;line-height:200%;font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">using conventional echocardiography and tissue Doppler imaging <span> ( </span>TDI) and compare the results with those of healthy control subjects. </span> <span style="font-size:10pt;line-height:200%;font-family:Arial, ’sans-serif’;color:#000000;"> </span> </p> <p> </p> <pre style="line-height:200%;background:#FFFFFF;"> <b> <span style="font-family:Arial, ’sans-serif’;color:#000000;">Materials and Methods: </span> </b> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">30 patients who were followed up with the diagnosis of MR due to sequel of rheumatic carditis </span> <span lang="en-gb" style="color:#000000;" xml:lang="en-gb"> </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">in our pediatric cardiology clinic and 30 healthy children aged between 5-15 years were included in the study. The patient group was categorized as mild-moderate MR (n: 20), and severe MR (n: 10). All echocardiographic and Doppler assessments were performed by a single expert pediatric cardiologist, who was blinded to the clinical and laboratory results of the study group </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;"> </span> </pre> <p> </p> <pre style="line-height:200%;background:#FFFFFF;"> <b> <span style="font-family:Arial, ’sans-serif’;color:#000000;">Results: </span> </b> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">LV end-diastolic diameters  were </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">significantly increased in patient with </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">severe MR </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">compared to controls </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb"> ( </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">4.62 ±0.82cm, 3.92±0.39cm; </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">p:0.008). Also LV end-systolic diameters were found </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">significantly increased in patient with </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">severe MR </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">compared to controls </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb"> ( </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">2.81±0.51, 2.43±0.25, </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">p:0.01). There was no statistically significant difference between groups in terms of LV ejection fraction and fractional shortening (p>0.05). </span> <span style="font-family:Arial, sans-serif;color:#000000;">Although </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">peak early diastolic myocardial </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">velocity </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;"> </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">obtained with TDI did not show significantly difference between the groups </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">(p>0.05), peak atrial systolic </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">velocity </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;"> </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb">measured from </span> <span style="font-family:Arial, ’sans-serif’;color:#000000;">the lateral and septal annulus </span> <span lang="en-gb" style="font-family:Arial, ’sans-serif’;color:#000000;" xml:lang="en-gb"> were significantly increased in patients with severe MR </span> <span style="font-family:Arial, ’sans-serif’;c}, number={1}, publisher={Rabia YILMAZ}