TY  - JOUR
TT  - Oxidative Stress in the Attack and Remission Periods of Schizophrenic Patients
AU  - Kılıç, Elif
AU  - Toprak, Aybala Erek
AU  - Ayhan, Sıddıka Kesgin
AU  - Baş, Alper
AU  - Duruyen, Saadettin
PY  - 2015
DA  - December
JF  - Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi
JO  - Gaziosmanpaşa Tıp Dergisi
PB  - Tokat Gaziosmanpaşa Üniversitesi
WT  - DergiPark
SN  - 1309-3320
SP  - 286
EP  - 298
VL  - 7
IS  - 4
KW  - Şizofreni
KW  - Oksidatif Stres
KW  - Total Antioksidan Seviye (TAS)
KW  - Total Oksidan Seviye (TOS)
N2  - Background: We aimed to investigate the relationship of oxidative stress and disease activity in patients with schizophrenia. Methods: Fifty seven patients diagnosed with schizophrenia and gender and age matched 54 controls were included in the study. Positive and negative syndrome scale (PANSS) was  used  for  general psychopathology whereas clinical global impressions scale (CGI-S),was used for measurement of functionality of patients. Total anti-oxidant (TAS) and total oxidant (TOS) status were analysed from the serums of patient and control groups. Results: There were  no  statistically significant difference between patient and control groups in age, gender, education level and smoking rates. TAS, TOS, oxidative stress index and demographic findings did not show significant difference in both groups regarding disease activity. There were no significant difference between positive and negative syndrome and clinical global impressions scales and oxidative stress parameters. Conclusions: The results obtained in our study did not show any difference in the value of  TOS  and  TAS  between schizophrenia and control groups. Besides, disease relationship of TAS and TOS levels between activity did  not  affect the
UR  - https://dergipark.org.tr/tr/pub/gutfd/article/378376
L1  - https://dergipark.org.tr/tr/download/article-file/403745
ER  -