TY - JOUR TT - Evaluation of The Low Risk Pregnant Women Who Gave Birth to Macrosomic Infants AU - Özgür Ersoy, Ali AU - Öztaş, Efser AU - Özler, Sibel PY - 2017 DA - December DO - 10.5799/jcei.382414 JF - Journal of Clinical and Experimental Investigations JO - J Clin Exp Invest PB - Aydın ECE WT - DergiPark SN - 1309-8578 SP - 114 EP - 119 VL - 8 IS - 4 KW - Birth weight KW - macrosomia KW - parity KW - pregnancy outcome N2 - ÖZETAmaç: Fetal makrozomi,maternal, fetal ve neonatal sağlığı etkileyen önemli bir faktördür.Çalışmamızın amacı, fetal makrozomiye yol açan maternal faktörleri ve gebeliksonuçlarını irdelemekti. Hastalar ve Yöntemler: Üçüncübasamak referans merkezi olan hastanemize miadında doğum için belirgin bir riskfaktörü olmadan başvuran, makrozomik bebek doğuran 348 kadın hasta çalışmagrubu, makrozomik olmayan bebek doğuran 474 hasta da kontrol grubu olarakaraştırmamıza dahil edildi. Gruplar arasında kişisel özellikler, laboratuvarözellikleri ve yenidoğan sağlığı açısından retrospektif olarak karşılaştırmayapıldı. Bulgular: Çalışmagrubundaki kadınların, yaşı, gebelik öncesi ve gebelik sonu vücut kitleendeksleri, gebelikte ağırlık artışı, önceki doğum sayısı kontrol grubuna görebelirgin olarak yüksekti. Bebeklerin doğum ağırlıkları, doğumun gerçekleştiğigebelik haftasıyla ve geçmiş doğum sayısı ile anlamlı pozitif korelasyongöstermekteydi. Açlık kan glukozu makrozomik bebek doğuran grupta belirginyüksekti. Sonuç: Makrozomik bebekdoğuran kadınlar, makrozomik doğurmayanlara göre daha ileri yaşta, daha obez,gebelikte daha fazla kilo almış, daha fazla sayıda doğum yapmış ve daha ilerigebelik haftasında doğurmuş kadınlardır. Diyabetik olmayan gebelerde de olsa,açlık glisemi düzeyi arttıkça bebek doğum ağırlığı artmaktadır. Neonatalhipoglisemi, hiperbilirubinemi riskleri ve yenidoğan yoğun bakım ihtiyacımakrozomi ile artmaktadır.  ABSTRACTObjective: Fetal macrosomia is an important entity that effectsmaternal, fetal and neonatal well-being. Our aim was to investigate thematernal factors which cause fetal macrosomia and to investigate the pregnancyoutcomes. Patients andMethods: Three hundredforty-eight low-risk women who attended to our tertiary care institution fordelivery and gave birth to a macrosomic infant were recruited as the studygroup, and 474 low-risk women who gave birth to a non-macrosomic infant wererecruited as the control group. Individual, laboratorial characteristics, andneonatal health variables were compared between two groups. Results: Maternal age, prepregnancy and peripartum body massindices, weight gain during pregnancy and parity values in the study group weremore than the control group. Birth weights of the babies correlatedsignificantly with gestational age at birth and parity values. Fasting bloodglucose levels of the mothers in the macrosomia group were significantly higherthan the control group. Conclusions: Women who gave birth to a macrosomic infant wereolder, more obese, gained more weight in the pregnancy period, had more parity,delivered at a later gestational age than women who gave birth to anon-macrosomic infant. Birth weight of the baby increases with increasingfasting blood glucose levels, even if the pregnant woman does not have any typeof diabetes in pregnancy. The risks of neonatal hypoglycemia andhyperbilirubinemia, and the need for neonatal intensive care unit were morefrequent in macrosomic infants. CR - 1. Alberico S, Montico M, Barresi V, Monasta L, Businelli C, Soini V, Erenbourg A, Ronfani L, Maso G; Multicentre Study Group on Mode of Delivery in Friuli Venezia Giulia. 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