@article{article_391097, title={Therapeutic Results Of Our Acromegalic Patients}, journal={Journal of Uludağ University Medical Faculty}, volume={29}, pages={39–45}, year={2003}, author={Ertürk, Erdinç and Tuncel, Ercan and Kıyıcı, Sinem and Ersoy, Canan and Duran, Cevdet and İmamoğlu, Şazi}, keywords={Akromegali, Oktreotid, Transsfenoidal Cerrahi, Hipopitüitarizm}, abstract={We aimed to evaluate our therapy results in acromegalic patients for last ten years. Although 52 acromegalic patients admitted to our center, only 30 (M/F: 13/17) patients whose follow-up data were available enrolled into the study. Their mean age was 43 ± 38 (28-64) years, mean age of diagnosis was 39 ± 9 (26-60) years and mean follow-up period was 42 ± 38 (5-127) months. Basal or nadir postglucose GH level less than 2 ng/ml accepted as cure criteria. After diagnosis, all patients operated transsphenoidally in different medical centers by different surgeons and the cure rate of first operation was 33 % (10/30). The cure rates were 63 % and 15 % in patients with microadenomas (n=11) and macroadenomas (n=19) respectively. And the difference was statistically significant (pIn conclusion cure rate probability was found higher in patients with microadenomas after transsphenoidal operation while it was very low in patients with macroadenomas. Our low cure rates could be attributed to the fact that the operations have been performed by inexperienced surgeons. While cure probability decreases after the second operation, complication risk increases. Octreotide therapy, which could be used as an alternative choice to the surgery, revealed high success rates in microadenomas and macroadenomas.}, number={3}, publisher={Bursa Uludağ Üniversitesi}