@article{article_391961, title={Thalassemia Intermedia}, journal={Journal of Uludağ University Medical Faculty}, volume={43}, pages={141–145}, year={2017}, author={Celkan, Tiraje and Kızılocak, Hande}, keywords={Globin defekti. Talasemi. Talasemi intermedia}, abstract={Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin, impaired alfa beta globin ratio, ineffective erythropoiesis and chronic anemia resulting in variable phenotypes ranging from severe anemia and transfusion dependency to clinically asymptomatic individuals. The term thalassemia intermedia refers to patients with clinical symptoms which are too mild than thalassemia major and too severe than thalassemia minor. Recent studies show that thalassemia intermedia is not as harmless as we think and is associated with organ dysfunctions, complications and high morbidity rate. For these problems, we want to mention iron chelation therapy, splenectomy, gall stones, hypercoagulability, pulmonary hypertension, growth retardation and other endocrine complications of these patients.}, number={3}, publisher={Bursa Uludağ Üniversitesi}