@article{article_392729, title={Endothelial dysfunction}, journal={Pamukkale Medical Journal}, pages={152–157}, year={2011}, url={https://izlik.org/JA46ZX26EE}, author={Yaylalı, Yalın Tolga and Küçükaslan, Mete}, keywords={Endotel fonksiyonları, endotel disfonksiyonu, ateroskleroz}, abstract={Endothelium is a multi-functional cluster of cells within the vascular system consisting of a single layer ofsquamous epithelium. Physiologically, endothelium performs various arrangement and protection functions.However, when these functions are disturbed toward derangement, endothelium also mediates pathologicalfunctions with negative effects on the body. Endothelial dysfunction is mediated by several mediators (nitricoxide, endothelins, prostaglandins, angiotensin 2, etc). Endothelial dysfunction implies a state in which mediatorsfunction, secretory disturbance is experienced, and some pathological factors are involved. It is suggested thatendothelial dysfunction can affect the course of chronic diseases, infl ammation, and atherosclerosis.}, number={3}