TY  - JOUR
TT  - The Relationship between Treatment Response and Histological Scoring Systems Applied in Chronic Hepatitis B
AU  - Abdullazade, Samir
AU  - Kav, Taylan
AU  - Gököz, Özay
AU  - Önder, Sevgen
AU  - Sökmensüer, Cenk
PY  - 2017
DA  - April
JF  - Kafkas Journal of Medical Sciences
JO  - KAFKAS TIP BİL DERG
PB  - Kafkas Üniversitesi
WT  - DergiPark
SN  - 2146-2631
SP  - 19
EP  - 25
VL  - 7
IS  - 1
KW  - viral hepatitis
KW  - scoring
KW  - HBV
N2  - In patients with chronic viral hepatitis liver biopsy has more important role in treatment planning than diagnostics. Nowadays, the role of liver needle biopsies is to provide a qualitative rather than a quantitative assessment of effects of viral hepatitis. For this qualitative assessment three scoring systems (Modified Knodell, METAVIR, Scheuer) are more widely used and the scoring results has become requisite in the pathology reports. The aim of this study is to identify the relationship between histopathological parameters of scoring systems applied in chronic viral hepatitis and treatment response; together with a comparison of these results with the literature. Material and Method: 101 patients diagnosed to have chronic B viral hepatitis and followed up for at least one year were included in the study. Patients were divided in two clinical groups according to the response to antiviral therapy. The relationship between treatment response and histological parameters of three scoring systems (Modified Knodell, Scheuer, METAVIR) used in chronic viral hepatitis were statistically evaluated. Results: There appeared to be a statistically significant relationship between the treatment response and METAVIR total grade A, METAVIR lobular activity in chronic B viral hepatitis. Conclusion: It can be claimed that METAVIR scoring system is better than Modified Knodell system for his-tological assessment in chronic B viral hepatitis.
UR  - https://dergipark.org.tr/tr/pub/kaftbd/issue//393719
L1  - https://dergipark.org.tr/tr/download/article-file/423706
ER  -