TY  - JOUR
TT  - CYTOTOXIC ACTIVITY OF PLATINUM(II) AND PLATINUM(IV) COMPLEXES BEARING 5(6)-NON/CHLOROSUBSTITUTED-2- HYDROXYMETHYL BENZIMIDAZOLE LIGANDS AGAINST HEp-2 CELL LINE :
AU  - Utku, Semra
PY  - 2007
DA  - March
DO  - 10.1501/Eczfak_0000000074
JF  - Journal of Faculty of Pharmacy of Ankara University
JO  - J. Fac. Pharm. Ankara
PB  - Ankara Üniversitesi
WT  - DergiPark
SN  - 1015-3918
SP  - 21
EP  - 30
VL  - 36
IS  - 1
KW  - Benzimidazol
KW  - Sitotoksik aktivite
KW  - HEp-2 hücre hattı
KW  - Platin(II) kompleksi
KW  - Platin(IV) kompleksi
N2  - In vitro cytotoxic activities of four platinum(II) and four platinum(IV) complexes with the structures [PtL2Cl2], [PtL2I2] and [PtL2Cl4], [PtL2Cl2(OH)2] (L= 5(6)-non/chloro-substituted-2hydroxymethyl benzimidazole ligands as “non-leaving groups”) respectively were tested on the human HEp-2 (larynx carcinoma) cell line using Cell Culture Method. In general the complexes, which were found to be more active than carboplatin exhibited moderate cyctotoxicity comparable to cisplatin on the human HEp-2 cell line
UR  - https://doi.org/10.1501/Eczfak_0000000074
L1  - https://dergipark.org.tr/tr/download/article-file/424445
ER  -