@article{article_394607, title={QUANTITATION OF ACETAMINOPHEN IN PHARMACEUTICAL FORMULATIONS USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY}, journal={Journal of Faculty of Pharmacy of Ankara University}, volume={27}, pages={93–100}, year={1998}, DOI={10.1501/Eczfak_0000000325}, author={Süzen, Sinan and Akay, Cemal and Tartılmış, Şenol and Erdöl R., Serdar and Önal, Atilla and Cevheroğlu, Şemsettin}, keywords={Asetaminofen, parasetamol, yüksek basınçlı sıvı kromatografisi, tablet, şurup}, abstract={A reversed-phase high-performance liquid chromatographic method has heen developed for the determination of acetaminophen in pharmaceutical formulations. A C18 stationary phase is used with a methanol-water (1/2, v/v) mixture at the flow rate of 1.78 ml/min with the spectrophotometric detection at 193.3 nm. Sulphamethoxazole is used as an internal standard and analysis is completed within 5 minutes. The method showed good linearity, precision and reproducibility. The proposed method was successfully applied to the determination of acetaminophen in tablet and syrup}, number={2}, publisher={Ankara Üniversitesi}