@article{article_400277, title={The co-evaluation of endosalpingeal karyorrhexis and salpingitis after the erythropoietin effect on fallopian ischemia reperfusion injury}, journal={Journal of Surgery and Medicine}, volume={2}, pages={65–68}, year={2018}, DOI={10.28982/josam.400277}, author={Constantinos, Tsompos and Constantinos, Panoulis and Konstantinos, Toutouzas and Aggeliki, Triantafyllou and George, C. Zografos and Apostolos, Papalois and Tsarea, Kalliopi and Karamperi, Maria}, keywords={İskemi,Eritropoietin,Endosalpingeal karyorrhexis,Salpenjit,Reperfüzyon}, abstract={<p class="MsoNormal" style="text-align:justify;"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">Aim: This study co-evaluated the 2 quoted histologic variables after the cytokine </span> <span class="A0"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">erythropoietin </span> </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;"> <span style="letter-spacing:-.05pt;">(Epo) administration. T </span> <span style="letter-spacing:-.15pt;">he calculation was based on the results of 2 preliminary studies, each one evaluating a respective histologic variable of </span> </span> <span class="A6"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;"> <span lang="en-gb" xml:lang="en-gb">endosalpingeal karyorrhexis </span> </span> </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;" lang="en-gb" xml:lang="en-gb"> </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">(EK) or </span> <span class="A0"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;"> salpingitis </span> </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;"> </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;letter-spacing:-.15pt;">(S) </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;letter-spacing:-.05pt;">in an induced ischemia reperfusion (IR) </span> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">animal <span style="letter-spacing:-.15pt;"> experiment </span>. </span> </p> <p class="MsoNormal" style="text-align:justify;"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">Methods: <span style="letter-spacing:-.15pt;"> The 2 main experimental endpoints at which the EK and S scores were evaluated, were </span> <span style="letter-spacing:-.1pt;">the reperfusion 60 <sup>th </sup> </span> <span style="letter-spacing:.2pt;">min </span> <span style="letter-spacing:-.05pt;">(for A & C groups </span> <span style="letter-spacing:-.2pt;">) </span> <span style="letter-spacing:-.05pt;"> </span> <span style="letter-spacing:-.1pt;">and </span> <span style="letter-spacing:.35pt;">the reperfusion </span> <span style="letter-spacing:-.15pt;">120 <sup>th </sup> </span> <span style="letter-spacing:.2pt;">min </span>(for B & D groups <span style="letter-spacing:-.2pt;">) </span>. Specially, the g <span style="letter-spacing:-.2pt;">roups </span>A <span style="letter-spacing:-.15pt;">and </span>B were processed without drugs, whereas the <span style="letter-spacing:-.2pt;">groups </span>C <span style="letter-spacing:-.15pt;">and </span> <span style="letter-spacing:.15pt;"> </span>D <span> after Epo </span>administration. <span style="letter-spacing:-.1pt;"> </span> </span> </p> <p class="MsoNormal" style="text-align:justify;"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">Results: The first preliminary study showed that Epo hardly non significantly increased the EK scores by the grade “without lesions” 0.0181818 [-0.0679319 - +0.1042955] (p-value=0.6715). The other preliminary study found that Epo did not influence the S scores (p-value=1.0000). Both studies were co-estimated since they belong to the same experimental setting. This study co-evaluated the combined diagnostic values of both variables together. </span> </p> <p class="MsoNormal" style="text-align:justify;"> <span style="font-size:11pt;font-family:’Times New Roman’, serif;">Conclusions: Epo again hardly non significantly increased both scores for these histologic parameters at <span>  </span>the grade of “without lesions” 0.0090909 [-0.0339659 - +0.0521478] (p-value=0.6715) since they were co-evaluated together. </span> </p>}, number={2}, publisher={Selçuk BAŞAK}