TY  - JOUR
T1  - Anthelmintic Activity of Ethanol Extract of Polygonum minus Leaves against Ascaridia galli
AU  - Maulidya, Dara Agusti
AU  - Kahtan, Muhammad Ibnu
AU  - Natalia, Diana
AU  - Handini, Mitra
AU  - Vidiyantoro, Ari
PY  - 2018
DA  - March
DO  - 10.5799/jmid.403142
JF  - Journal of Microbiology and Infectious Diseases
JO  - J Microbil Infect Dis
PB  - Aydın ECE
WT  - DergiPark
SN  - 2146-3158
SP  - 23
EP  - 26
VL  - 08
IS  - 01
LA  - en
AB  - Anthelmintic Activity of EthanolExtract of Polygonum minus Leaves againstAscaridia galliDara AgustiMaulidya1, Muhammad Ibnu Kahtan2, Diana Natalia2,Mitra Handini3, Ari Widiyantoro41University of Tanjungpura, Facultyof Medicine,  Pontianak, West Kalimantan, Indonesia2University of Tanjungpura, Facultyof Medicine, Department of Parasitology, Pontianak, West Kalimantan, Indonesia3University of Tanjungpura, Facultyof Medicine, Department of Physiology, Pontianak, West Kalimantan, Indonesia4University of Tanjungpura, Facultyof Mathematics and Science, Department of Chemistry, Pontianak, WestKalimantan, IndonesiaABSTRACTObjectives: Helminth infection is one of the main matters thatcause health problems in developing countries. Polygonum minus are empirically used as an anthelmintic drug, butthere has been no scientific study that proves it. Methods: Thisstudy was aimed at determining the anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli in vitro. The extractwas prepared in three different concentrations i.e 0.5 mg/mL, 1 mg/mL and 2mg/mL. NaCl 0.9% was used as a negative control group and albendazole 0.2mg/mL, a broad spectrum anthelmintic was used as a positive control group. Ascaridia galli was used as the testparasite. The study involved the determination of death time of the worms. Results: Thedeath time of the worms that caused by the extract concentration 0.5 mg/mL, 1mg/mL and 2 mg/mL, respectively were (mean±SD) 35±3.32 hours, 32.8±2.39 hoursand 25±3.39 hours. The death time that caused by negative and positive controlgroup were 76.6±8.30 hours and 19.2±1.48 hours. There is no significantdifference of death time of the worms between the extract concentration 2 mg/mLand the positive control group. Conclusion: The anthelmintic activity of ethanol extract of Polygonum minus leaves has beenconfirmed and extract concentration 2 mg/mL has the same anthelmintic activitywith albendazole 0.2 mg/mL. J MicrobiolInfect Dis 2018; 8(1):23-26Keywords:Anthelmintic, Polygonum minus, Ascaridiagalli, ascariasis
KW  - Anthelmintic
KW  - Polygonum minus
KW  - Ascaridia galli
KW  - ascariasis
CR  - REFERENCES
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UR  - https://doi.org/10.5799/jmid.403142
L1  - https://dergipark.org.tr/tr/download/article-file/437155
ER  -