TY  - JOUR
TT  - OVER NEOPLAZİLERİNDE ANGİOGENESİS VE NEOVASKÜLARİZASYONUN ARAŞTIRILMASI
AU  - Koç, Önder
AU  - Zergeroğlu, Sema
AU  - Duran, Bülent
AU  - Koç, Ümmügülsüm
AU  - Topçuoğlu, Ata
AU  - Kesim, Melahat
PY  - 2007
DA  - April
JF  - Türk Jinekolojik Onkoloji Dergisi
JO  - TRSGO Dergisi
PB  - Türk Jinekolojik Onkoloji Derneği
WT  - DergiPark
SN  - 2148-5372
SP  - 45
EP  - 50
VL  - 10
IS  - 2
KW  - Ovarian neoplasia
KW  - angiogenesis
KW  - vascularisation
KW  - faktör VIII
KW  - CD 31
N2  - Objective: We aimed to find neovascularization in 100 ovarian neoplasia cases by using immunohistochemical method with primary antibody F VIII and CD 31 in Zekai Tahir Burak Education and Research Hospital Material and method: Cases were stained by using immunohisto-chemical method with FVIII and CD 31. 78 of the cases were epithelial ovarian cancer. 9 of the cases were germ cell tumor followed by 8 cases of sex cord stromal tumor and 5 cases of krukenberg tumor. Lymph node dissection were performed in 85 of the cases and 25 of them were positive. During the clinical follow up 10 cases were died, recurrrences were seen in 8 cases and remission were found in 11 cases. Results: Immunhistochemical staining of microvessel density by using F VII antibody showed significant relation with tumor grade. But there were no relation with tumor type, lymph node positivity, tumor remission and tumor recurrence. Immunhistochemical staining of microvessel density by using CD 31 antibody showed no relation with tumor type. Conclusion: CD 31 as an angiogenetic marker showed more prognostic importance than the other marker. This study showed angio-genetic markers are important agents in prediagnosis of tumor progression. Trial series of this markers with more cases
UR  - https://dergipark.org.tr/tr/pub/trsgo/issue//404434
L1  - https://dergipark.org.tr/tr/download/article-file/439182
ER  -