TY  - JOUR
T1  - Tuberous sclerosis complex
TT  - Tuberoskleroz Kompleksi
AU  - Ünlütürk, Zeynep
AU  - Tekin, Selma
AU  - Değirmenci, Eylem
AU  - Kaçar, Nida
PY  - 2018
DA  - April
JF  - DOD Clinical Case Reports
JO  - DODCR
PB  - Dermatoonkoloji Derneği
WT  - DergiPark
SN  - 2618-6624
SP  - 9
EP  - 12
VL  - 2
IS  - 1
LA  - en
AB  - Tuberous sclerosis (TS) is an autosomal dominant disordercharacterized mainly by mental retardation, epilepsy and adenoma sebasemiatriad. All triads can be detected in only one third of the patients. Tuberoussclerosis complex (TSC) is a hamartomatosis that mainly carries the centralnervous system, skin, retina, kidney and heart. Pathologies associated withrenal involvement in patients with tuberous sclerosis; angiomyolipomas(70-80%), renal cysts (20%) and very rarely cancers. The most common neurologicalfinding is epileptic seizures In this article, we present a case report of a patient who appliedto dermatological clinic with acne compleints and diagnosed as a tuberoussclerosis complex with skin findings, cortical tuber and angiomyolipoma inaddition to radiological examinations.
KW  - tuberous sclerosis
KW  - çocuk
KW  - acne
N2  - Tuberoskleroz(TS) başlıca mental retardasyon, epilepsi ve adenoma sebaseum triadı ilekarakterize otozomal dominant geçişli bir hastalıktır. Tüm triad hastalarınancak üçte birinde saptanabilmektedir. Tuberoskleroz kompleksi(TSK), başlıca santral sinir sistemi, deri, retina, böbrek ve kalbi tutan birhamartomatozistir. Tuberosklerozlu hastalarda böbrek tutulumu ile ilişkilipatolojiler; angiomyolipom (%70–80), renal kist (%20) ve çok nadiren kanserlerolup en sık görülen nörolojik bulgu ise epileptik nöbetlerdir.Buyazıda, yüzde sivilce yakınması ile dermatoloji polikliniğine başvuran deribulguları ile tuberoskleroz kompleksi tanısı düşünülen, radyolojik incelemelerleek olarak kortikal tuber ve anjiyomiyolipom saptanan bir olgu sunuma değerbulunmuştur.
CR  - 1.	Rosser T, Panigrahy A, McClintock W. The diverse clinical manifestations of tuberous sclerosis complex: a review. Semin Pediatr Neurol. 2006;13: 27-36.
CR  - 2.	Morris BS, Garg A, Jadhav PJ. Tuberous sclerosis: A presentation of less-commonly encountered stigmata. Austral Radiol. 2002; 46: 426-30.
CR  - 3.	Patel SB, Shah SS, Goswami K, Shah N, Pandhi S. Case report: Tuberous sclerosisit’s varied presentation. Ind J Radiol Imag. 2004; 14: 423-5.
CR  - 4.	Harper JI. Tuberous sclerosis complex. In: Champion RH, Burton JL, Burns DA, Breathnanh SM eds. Textbook of Dermatology. 6th ed. United Kingdom: Blackwell Science 1998:384-8.
UR  - https://dergipark.org.tr/tr/pub/dccr/issue//410502
L1  - https://dergipark.org.tr/tr/download/article-file/469522
ER  -