TY  - JOUR
T1  - Developing Hemophagocytic Syndrome during the transformation of Chronic Lymphocytic Leukemia: Case reports of t(7;14), t(14;19) and deletion of 17 p
AU  - Tiryaki, Tarik Onur
AU  - Genc, Sezen
AU  - Ozan, Gulcin Bagatir
AU  - Cefle, Kivanc
AU  - Palanduz, Sukru
AU  - Yegen, Gulcin
AU  - Dogan, Oner
AU  - Nalcaci, Meliha
PY  - 2018
DA  - April
DO  - 10.17546/msd.413622
JF  - Medical Science and Discovery
JO  - Med Sci Discov
PB  - Zafer AKAN
WT  - DergiPark
SN  - 2148-6832
SP  - 188
EP  - 191
VL  - 5
IS  - 5
LA  - en
AB  - Chroniclymphocytic Leukemia (CLL) is the most common form of leukemia in adults.Clinical findings may broad range vary. Detecting some deletions using the FISHmethod may help us to foresee the progression of the disease and to choose abetter treatment method in healing the patient. In this case report, we willpresent you a CLL patient with t(7;14), t(14;19) and 17p deletions, which are known for badprognosis, developing autoimmune hemolytic anemia which is refractor to thetreatment. This patient unfortunately died due to a clinical form ofhemophagocytic syndrome including prolymphocytic transformation.
KW  - Chronic Lymphocytic Leukemia
KW  - Hemophagocytic Syndrome
KW  - hematologic malignancies
KW  - t(7;14)
KW  - t(14;19)
KW  - 17p
KW  - deletion
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UR  - https://doi.org/10.17546/msd.413622
L1  - https://dergipark.org.tr/tr/download/article-file/475307
ER  -