TY - JOUR T1 - Santral venöz portların çıkarılma nedenleri: Ardışık 154 hastadan edinilen deneyim TT - Reasons for removal of central venous ports: Experience with 154 consecutive patients AU - Uzunkaya, Fatih AU - Soylu, Ayşegül İdil AU - Belet, Ümit AU - Terzi, Özlem AU - Akan, Hüseyin PY - 2018 DA - December DO - 10.19161/etd.417318 JF - Ege Tıp Dergisi JO - EJM PB - Ege Üniversitesi WT - DergiPark SN - 1016-9113 SP - 232 EP - 237 VL - 57 IS - 4 LA - tr AB - Amaç: Bu çalışmanın amacı, tek merkezde santral venözportların çıkarılma nedenlerinin sıklıklarını tespit etmek, port kaynaklı enfeksiyonile ilişkili risk faktörlerini ve portların açık kaldığı süreyi etkileyenfaktörleri belirlemektir.Gereç ve Yöntem: Ocak 2005 -Mayıs 2017 tarihleri arasında port çıkarma işlemi yapılmış 154 hasta çalışmayadahil edildi. Hastaların yaş ve cinsiyetleri, klinik tanıları, portlarınınçıkarılma nedenleri, mikrobiyolojik test sonuçları ve portlarının açık kaldığısüreler retrospektif olarak araştırıldı. Port kaynaklı enfeksiyon ile ilişkilirisk faktörlerini karşılaştırmak için Ki-kare testi, portların açık kaldığısüreyi etkileyen faktörleri karşılaştırmak için ise Mann-Whitney U testikullanıldı.Bulgular: Hastaların %51.3’ü kadın, %48.7’si erkekti (yaş ortalaması, 55.1±15).Portların en sık (%53.2) enfeksiyon gerekçesiyle çıkarıldığı tespit edildi. Cinsiyetin,yaşın, malignite tipinin ve sindirim kanalı kanserine sahip olmanın enfeksiyonsıklığını anlamlı derecede etkilemediği belirlendi. Enfeksiyon gelişenhastaların kültürlerinde en sık (%20.9) izole edilen patojenin Staphylococcus aureus olduğu görüldü.Cinsiyetin, yaşın, malignite tipinin ve sindirim kanalı kanserine sahip olmanınportların açık kaldığı süreyi anlamlı derecede etkilemediği, buna karşınenfeksiyonun bu süreyi önemli ölçüde kısalttığı tespit edildi.Sonuç: Kanser hastalarının yarısından fazlasının portu enfeksiyon nedeniyleçıkarılmaktadır. Enfeksiyon, portların açık kaldığı süreyi önemli ölçüdekısaltmaktadır. KW - Santral venöz port KW - girişimsel radyoloji KW - kanser KW - enfeksiyon. N2 - Aim: The aim of this study is to determine thefrequency of reasons for port removal in a single center, to identify the risk factors associated withport-related infection and the factors that affect the patency period of theports.Materials and Methods:154 patients with portremoval from January 2005 to May 2017 were included in the study. Thecharacteristics of these patients, their clinical diagnoses, reasons for portremoval, microbiological data and patency periods were retrospectivelyinvestigated. The Chi-square test was used to compare the risk factorsassociated with port-related infection, and the Mann-Whitney U test was used tocompare the factors affecting the patency period.Results: 51.3% of the patients were female, 48.7% weremale (mean age, 55.1±15). The most frequent (53.2%) reason for port removal wasfound to be infection. It was determined that gender, age, malignancy type andhaving digestive tract cancer did not affect the infection frequencysignificantly. The most common pathogen (20.9%) was found to be Staphylococcus aureus in the cultures of infected patients. It was found that gender, age,malignancy type and having digestive tract cancer did not significantly affectthe patency period of the ports, however, infection significantly shortenedthis period.Conclusion: Ports are removed due toinfection in more than half of the patients with cancer. Infectionsignificantly shortens the patency period of ports. CR - Ji L, Yang J, Miao J, Shao Q, Cao Y, Li H. Infections related to totally implantable venous-access ports: Long-term experience in one center. Cell Biochem Biophys 2015;72(1):235-40. CR - Lebeaux D, Larroque B, Gellen-Dautremer J, et al. Clinical outcome after a totally implantable venous access port-related infection in cancer patients: A prospective study and review of the literature. Medicine 2012;91(6):309-18. CR - Biacchi D, Sammartino P, Sibio S, et al. Does the implantation technique for totally implantable venous access ports (TIVAPs) influence long-term outcome? World J Surg 2016;40(2):284-90. CR - Kurul S, Saip P, Aydin T. Totally implantable venous-access ports: Local problems and extravasation injury. Lancet Oncol 2002;3(11):684-92. CR - Barbetakis N, Asteriou C, Kleontas A, Tsilikas C. Totally implantable central venous access ports. Analysis of 700 cases. J Surg Oncol 2011;104(6):654-6. CR - Fischer L, Knebel P, Schröder S, et al. Reasons for explantation of totally implantable access ports: A multivariate analysis of 385 consecutive patients. Ann Surg Oncol 2008;15(4):1124-9. CR - Hsieh CC, Weng HH, Huang WS, et al. Analysis of risk factors for central venous port failure in cancer patients. World J Gastroenterol 2009;15(37):4709-14. CR - Chang L, Tsai JS, Huang SJ, Shih CC. Evaluation of infectious complications of the implantable venous access system in a general oncologic population. Am J Infect Control 2003;31(1):34-9. CR - Hickman RO, Buckner CD, Clift RA, Sanders JE, Stewart P, Thomas ED. A modified right atrial catheter for access to the venous system in marrow transplant recipients. Surg Gynecol Obstet 1979;148(6):871-5. CR - Broviac JW, Cole JJ, Scribner BH. A silicone rubber atrial catheter for prolonged parenteral alimentation. Surg Gynecol Obstet 1973;136(4):602-6. CR - Vidal M, Genillon JP, Forestier E, et al. Outcome of totally implantable venous-access port-related infections. Med Mal Infect 2016;46(1):32-8. CR - Schwarz RE, Groeger JS, Coit DG. Subcutaneously implanted central venous access devices in cancer patients: A prospective analysis. Cancer 1997;79(8):1635-40. CR - Kock HJ, Pietsch M, Krause U, Wilke H, Eigler FW. Implantable vascular access systems: Experience in 1500 patients with totally implanted central venous port systems. World J Surg 1998;22(1):12-6. CR - Shim J, Seo TS, Song MG, et al. Incidence and risk factors of infectious complications related to implantable venous-access ports. Korean J Radiol 2014;15(4):494-500. CR - Lebeaux D, Fernández-Hidalgo N, Chauhan A, et al. Management of infections related to totally implantable venous-access ports: challenges and perspectives. Lancet Infect Dis 2014;14(2):146-59. CR - Penel N, Neu JC, Clisant S, Hoppe H, Devos P, Yazdanpanah Y. Risk factors for early catheter-related infections in cancer patients. Cancer 2007;110(7):1586-92. CR - Vescia S, Baumgärtner AK, Jacobs VR, et al. Management of venous port systems in oncology: A review of current evidence. Ann Oncol 2008;19(1):9-15. CR - Groeger JS, Lucas AB, Thaler HT, et al. Infectious morbidity associated with long-term use of venous access devices in patients with cancer. Ann Intern Med 1993;119(12):1168-74. CR - Chen WT, Liu TM, Wu SH, Tan TD, Tseng HC, Shih CC. Improving diagnosis of central venous catheter-related bloodstream infection by using differential time to positivity as a hospital-wide approach at a cancer hospital. J Infect 2009;59(5):317-23. CR - Aribas BK, Tiken R, Aribas O, et al. Factors on patency periods of subcutaneous central venous port: long-term results of 1.408 patients. Iran J Radiol 2017;14(2):e36816. UR - https://doi.org/10.19161/etd.417318 L1 - https://dergipark.org.tr/tr/download/article-file/461140 ER -