TY  - JOUR
T1  - A REVIEW ON THE HYDROGELS USED IN 3D BIO-PRINTING
TT  - 3D BIYO-YAZICILARDA KULLANILAN HİDROJELLER ÜZERİNE BİR İNCELEME
AU  - Topuz, Mehmet
AU  - Dikici, Burak
AU  - Gavgalı, Mehmet
AU  - Yılmazer, Hakan
PY  - 2018
DA  - July
JF  - International Journal of 3D Printing Technologies and Digital Industry
JO  - IJ3DPTDI
PB  - Kerim ÇETİNKAYA
WT  - DergiPark
SN  - 2602-3350
SP  - 68
EP  - 75
VL  - 2
IS  - 2
LA  - en
AB  - The bio-printingprocess describes asa computer-aided transfer process for printing of biological structures such as cells and biomaterials to fabricate medicalconstructions for different medical fields (tissue engineering, regenerativemedicine, or other biological studies). Especially, three-dimension (3D) bio-printing technology is used to print livingorgans like livers, kidneys, lungs, and any other organs in the body. Hydrogels have been widely used in 3D bio-printingto load cell for tissue engineering due to their high biocompatibility. Inaddition, hydrogels simulate the soft tissues which present in the body,swollen in water at high levels and have similar mechanical properties to thoseof natural soft tissues, many researchers have been interested in hydrogels andtheir reputations are increasing day by day. They are generally divided intotwo groups as (i) natural hydrogels and (ii) synthetic hydrogels. Key documentsin the literature about both natural and synthetic hydrogels have been reviewedin this study. Also, 3D bio-printing process of the hydrogels has been discussed as detailly.
KW  - 3D Printer
KW  - Bio-printing
KW  - Hydrogels
N2  - Biyo-yazıcı işlemi,farklı tıbbi alanlarda (doku mühendisliği, rejeneratif tıp veya diğer biyolojikçalışmalar) tıbbi yapıları imal etmek için hücreler ve biyomateryaller gibibiyolojik yapıların üretilmesi için bilgisayar destekli bir transfer işlemiolarak tanımlanmaktadır. Üç boyutlu (3D) bio-yazıcı teknolojisi, özelliklekaraciğer, böbrekler, akciğerler ile vücuttaki diğer canlı organlar ile diğerorganların yazdırılmasında kullanılır. Hidrojeller, yüksek biyo-uyumluluklarınedeniyle doku mühendisliği için hücre yüklemek için 3D biyo-yazıcıda yaygınolarak kullanılmaktadır. Buna ek olarak, hidrojeller vücutta bulunan yumuşakdokuları simüle etmesi, suda yüksek oranda şişebilme kaabiliyeti ve doğal yumuşakdokularınki ile benzer mekanik özelliklere sahip olmasından dolayı birçokaraştırmacı hidrojel ile ilgilenmiştir ve onlara olan ilgi her geçen günartmaktadır. Genellikle (i) doğal hidrojeller ve (ii) sentetik hidrojel olarakiki gruba ayrılırlar. Bu çalışmada hem doğal hem de sentetik hidrojellerhakkında literatürdeki önemli belgeler derlenmiş olup ek olarak, hidrojellerin3D biyo-yazıcı işlemi detaylı bir şekilde tartışılmıştır.
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UR  - http://dergipark.org.tr/tr/pub/ij3dptdi/issue//419806
L1  - http://dergipark.org.tr/tr/download/article-file/501547
ER  -