TY - JOUR T1 - Detection of Ochratoxin A In Bulk Tank Milk TT - Süt Toplama Tanklarında Okratoksin A Varlığının Belirlenmesi AU - Keyvan, Erhan AU - Yurdakul, Ozen AU - Kocasarı, Fatma AU - Tutun, Hidayet AU - Demirtaş, Ahu AU - Kahraman, Hatice Ahu AU - Şen, Erdi PY - 2018 DA - September Y2 - 2018 DO - 10.30607/kvj.424808 JF - Kocatepe Veterinary Journal JO - kvj PB - Afyon Kocatepe Üniversitesi WT - DergiPark SN - 1308-1594 SP - 255 EP - 259 VL - 11 IS - 3 LA - en AB - Ochratoxin A (OTA) produced by several Aspergillus and Penicillium species is a mycotoxin that contaminates differentfoods and feedstuffs, including cereals, coffee beans, nuts, cocoa, pulses,beer, wine, spices, dried vine fruits, meat, milk. In humans and animals, OTAhas been observed to be particularly nephrotoxic, hepatotoxic, immunotoxic,neurotoxic, embryotoxic, carcinogenic and teratogenic. Ochratoxin A is a stablemolecule and can remain unchanged even after the processes applied. In thisstudy, it was aimed to determine the presence of ochratoxin A in milk samples(n:40) collected from bulk tank milks in Burdur province of Turkey. Thepresence of OTA in the samples was analyzed by using ELISA. The analyzes wereperformed according to the manufacturer's instructions. As a result, OchratoxinA was found in 40 cow’s milk samples (range 2-270 ng/l) collected from bulkmilk tanks. The results of this study show that cow’s milk should be consideredas a potential OTA source in the human diet. It is proposed to examine thepresence of OTA more intensively in dairy products and to determine theirmaximum limit values by conducting necessary studies. KW - Burdur KW - Ochratoxin A KW - Milk KW - Micotoxin N2 - Okratoksin A (OTA), Aspergillus ve Penicillium türü mantarlar tarafından sentezlenen ve tahıl, kahveçekirdeği, fındık, kakao, bakliyat, bira, şarap, baharat ve kuru üzümdebulunabilen bir mikotoksindir. İnsanlarda ve hayvanlarda, OTA özelliklenefrotoksik, hepatotoksik, nörotoksik, embriyotoksik, immunotoksik, teratojenikve karsinojenik etkiler gösterir. Okratoksin A kısmen kararlı bir moleküldür vegıdalara uygulanan işlemlerden sonra bile değişmeden kalabilir. Bu çalışmada;Burdur bölgesinde bulunan süt toplama tanklarında (n:40) OTA varlığınınbelirlenmesi amaçlandı. Örneklerde OTA varlığı ELISA kullanılarak analizedildi. Analizler üreticinin talimatlarına göre yapıldı. Süt toplama tanklarındanalınan 40 inek süt örneğinde (2-270 ng/l aralığında) OTA bulundu. Bu çalışmanınsonuçları, inek sütünün insan beslenmesinde potansiyel bir OTA kaynağı olarakgörülmesi gerektiğini göstermektedir. OTA varlığını süt ürünlerinde daha yoğunbir şekilde incelenmesi ve gerekli mevzuat çalışmaları yapılarak maksimum limitdeğerlerinin belirlenmesi önerilmektedir. CR - Alshannaq A, Yu JH. Occurrence, toxicity, and analysis of major mycotoxins in food. Int J Environ Res Public Health. 2017; 14(6): 632. 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