@article{article_433800, title={The Impact of Serum Vitamin D Concentration on Median Nerve Conduction}, journal={Journal of Clinical and Experimental Investigations}, volume={9}, pages={63–66}, year={2018}, DOI={10.5799/jcei.433800}, author={Özer, Gökhan}, keywords={25-hydroxyvitamin D,median nerve,conduction}, abstract={ Objectives: To perform nerve conduction studies (NCS) and to evaluate distal latency, amplitude and conduction velocity values of the median nerve in relation to serum vitamin D levels in patients with neuropathic symptoms compared to controls. <o:p> </o:p> Patients and Methods: Patients with neuropathic symptoms of numbness, tingling and burning sensation were included in the study. Serum 1,25(OH) D3 levels were measured and patients were stratified by vitamin D status into three subgroups. Electrophysiological assessments of the median nerve were performed as recommended by the American Society of Electrodiagnostic Medicine . SPSS for Windows, version 24 was used for statistical analyses. Median nerve conduction values were compared between patient and control groups in relation to vitamin D concentration. <o:p> </o:p> Results: The study enrolled 39 patients including 24 (61.5%) males and 15 (38.5%) females and 39 control subjects including 22 (56.4%) males 17 (43.6%) females. Patient and control groups had a mean age of 45 years. Average vitamin D concentration was 8.5 ng/ml in the patient group and 8.8 ng/ml in the control group. There was no statistically significant difference between two groups with respect to age and average vitamin D concentration (p=0.552). Greater distal latency values and a statistically significant association between median nerve distal latency and vitamin D deficiency were found in the vitamin D-deficient subgroup (p=0.024). <o:p> </o:p> Conclusion: Given the neuroprotective action of vitamin D and the involvement of vitamin D deficiency in several neurological diseases as well as evidence that it might be an independent risk factor and a potential biomarker for neuropathy, we believe that patients presenting with mononeuropathy or polyneuropathy to a healthcare facility should be screened for vitamin D deficiency.  <o:p> </o:p> }, number={2}, publisher={Aydın ECE}