@article{article_433812, title={Evaluation of relationship between digit ratio (2D: 4D) and epilepsy: Can 2D:4D be a clue for epileptogenesis?}, journal={Journal of Clinical and Experimental Investigations}, volume={9}, pages={87–90}, year={2018}, DOI={10.5799/jcei.433812}, author={Akdeniz, Gülsüm}, keywords={Digit ratio,2D:4D,Edinburg handedness test,epilepsy,hand}, abstract={<div>Objective: The aim of the study was to investigate the possible association between the 2D:4D </div> <div>ratio and epilepsy in male and female adults, and to compare the ratios of epilepsy patients and </div> <div>healthy control subjects. </div> <div>Patients and Methods: A case-control study carried out at a neurology and biophyiscs </div> <div>department in Ankara Yıldırım Beyazıt University, Faculty of Medicine from May 2016 to January </div> <div>2017. The 2D:4D ratios of both the left and right hands of 172 epilepsy patients and 202 </div> <div>matched healthy controls were recorded. All participants also completed the Edinburgh </div> <div>handedness inventory. </div> <div>Results: A significant positive correlation between the 2D:4D ratio and epilepsy was found for </div> <div>both females and males; a lower ratio for the left hand was associated with a higher possibility </div> <div>of epilepsy. In addition, a lower ratio in a specific hand was associated with that hand being </div> <div>used to complete the handedness test. </div> <div>Conclusions: The 2D:4D ratio serves as a predictor for increased risk of epilepsy. Thus, it could </div> <div>be used as a marker to differentiate patients with epilepsy from healthy controls. </div>}, number={2}, publisher={Aydın ECE}