@article{article_435075, title={Neuropathic pain adversely affects functional status, quality of life and depression in patients with knee osteoarthritis}, journal={Ortadoğu Tıp Dergisi}, volume={11}, pages={15–21}, year={2019}, DOI={10.21601/ortadogutipdergisi.435075}, author={Koçyiğit, Burhan Fatih and Koca, Tuba Tülay}, keywords={diz osteoartriti,nöropatik ağrı,fonksiyonel durum,yaşam kalitesi,depresyon}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Aim: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">
The aim of our study was to determine the existence of neuropathic pain (NP) in
knee OA and its association with risk factors, functional status, quality of
life, and depression. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Material
and Methods: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> This was a descriptive study. A
total of <b> </b>100 patients (90 female, 10
male) with knee OA were enrolled. Data including age, gender, educational
status, working status, body mass index, and symptom duration were obtained
from patients. </span> <span lang="en-us" xml:lang="en-us"> </span> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Patients
were divided into three groups according to the PainDETECT scores: likely NP,
possible NP, unlikely NP. </span> <span lang="en-us" xml:lang="en-us"> </span> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Patients’
pain severity was assessed using visual analogue scale (VAS). For the presence
of NP, PainDETECT scale was used. Functional status was evaluated by Western
Ontario and McMaster University Osteoarthritis Index (WOMAC). Quality of life
was assessed using Short Form-36 questionnaire (SF-36) and depression level was
evaluated using Hamilton Depression Scale (HAM-D). Kellgren-Lawrence grading
system was used to determine the radiologic severity. </span> <span lang="en-us" xml:lang="en-us"> </span> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Pain,
functional status, quality of life and depression were compared among the
groups. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Results: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us"> Of the total, </span> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">18 patients (18%) were
in the likely NP group; 23 patients (23%) were in the possible NP group and 59
(59%) patients were in the unlikely NP group. </span> <span lang="en-us" xml:lang="en-us"> </span> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">No
significant differences were detected between the groups in sociodemographic
data (p > 0.05). Significant differences were detected in symptom duration, VAS,
WOMAC, SF-36 physical functioning subscale, physical role functioning subscale,
social role functioning subscale, vitality subscale, bodily pain subscale,
general health perceptions subscale and HAM-D scores among the groups (p <
0.05). PainDETECT scores were significantly correlated with VAS, WOMAC, SF-36
subscales, and HAM-D (p < 0.05). </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">Conclusion: </span> </b> <span lang="en-us" style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;" xml:lang="en-us">
This study revealed that NP is associated with severe pain, reduced
functionality, impairment in quality of life, and higher depression scores in
patients with knee OA.  </span> </p> <p> </p> <p> </p>}, number={1}, publisher={MEDİTAGEM Ltd. Şti.}