TY  - JOUR
T1  - Effects of Aflatoxin on Kidney and Protective Effectiveness of  Esterified Glucomannan in Ram
TT  - Koçlarda Aflatoksinin Böbrek Üzerine Etkileri ve Esterifiye Glukomannanın Koruyucu Etkinliği
AU  - Çolakoğlu, Fatma
AU  - Dönmez, Hasan Hüseyin
PY  - 2017
DA  - April
Y2  - 2016
JF  - Van Veterinary Journal
JO  - Van Vet J
PB  - Van Yüzüncü Yıl Üniversitesi
WT  - DergiPark
SN  - 2149-3359
SP  - 37
EP  - 40
VL  - 28
IS  - 1
LA  - en
AB  - In this study, the effects of total aflatoxin (AF) given orally onkidney in Merino rams were studied. In addition, this study was conducted inorder to evaluate the efficacy of an esterified glucomannan (EG) for protectionagainst to aflatoxicosis. One year-old 32 Merino rams were divided into fourequal groups. Rams were fed through the 92 days. Control group (C) fed with thecommercial feed. AF group fed with commercial feed added 250 µg/day of total AF. EG group fed with commercial feed added 2g/day of EG. AF+EG group fed with commercial feed added 250 µg/day of total AFand 2 g/day of EG. At the end of the 92 day after cessation of theanimals, tissue samples were taken from the kidney in order to performhistological structure. Degeneration and spills in the tubular epithelial cellsof kidney were observed in the AF group. Massive hyperemia was observed in therenal vessels. In conclusion, the adverse effects causing by aflatoxicosis onthe kidney could be ameliorated by adding EG to the ration.
KW  - Aflatoxin
KW  - Glucomannan
KW  - Kidney Histology
KW  - Ram
N2  - Buçalışmada Merinos ırkı koçlara ağızdan verilen total aflatoksinin (AF) böbreküzerine etkileri ile glukomannanın (EG) koruyucu etkinliği değerlendirildi.Çalışmada 1 yaşında 32 adet koç 4 eşit gruba ayrıldı. Beslemeye 92 gün devamedildi. Kontrol (K) grubuna ticari yem; AF grubuna ticari yem ile günlük 250 µgAF; EG grubuna ticari yem ile günlük 2 gr EG; AF+EG grubuna ise ticari yemlebirlikte günlük 250 µg AF ve 2 gr EG verildi. 92. günün sonunda hayvanlar kesildikten sonra böbrekteki histolojikyapıyı göstermek için örnekler alındı. AF grubunun böbrek tübüllerindedejenerasyon ve dökülmeler, böbrek damarlarında ise yoğun hiperemi gözlendi. Sonuç olarak; aflatoksikozun böbrek üzerindeki olumsuzetkilerinin yeme EG ilave edilerek iyileştirilebildiği ortaya konmuştur.
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UR  - https://dergipark.org.tr/tr/pub/vanvetj/issue//436585
L1  - https://dergipark.org.tr/tr/download/article-file/493950
ER  -