TY  - JOUR
T1  - Giant Cell Carcinoma of the Lung: Management of Surgical Treatment
TT  - Akciğerin dev hücreli tümörü: cerrahi tedavi yönetimi
AU  - İncekara, Funda
AU  - Sayılır Güven, Ebru
AU  - Demiröz, Şevki Mustafa
AU  - Şengül İnan, Merve
AU  - Aydoğdu, Koray
AU  - Demirağ, Funda
AU  - Gülhan, Selim Şakir Erkmen
AU  - Kaya, Sadi
AU  - Fındık, Göktürk
PY  - 2019
DA  - June
DO  - 10.21601/ortadogutipdergisi.440816
JF  - Ortadoğu Tıp Dergisi
JO  - omj
PB  - MEDİTAGEM Ltd. Şti.
WT  - DergiPark
SN  - 2548-0251
SP  - 125
EP  - 130
VL  - 11
IS  - 2
LA  - en
AB  - Objectives: Pulmonary giant cell carcinoma (PGCC) is ahistological type of nonsmall cell lung cancer and classified as one of the fivesubtypes of sarcomatoid carcinoma of the lung. Pure PGCC is very rare. Material and Method: We represent our experience in the managementof 7 patients (6 males and 1 female, with a range of 44-63 yr) with PGCC. The mostrepresenting symptoms were cough and hemoptysis. Upper lobectomy (n=7) and additionallymediastinal lymphadenectomy were performed in all patients.Results: Definitive histological examination confirmedthe diagnosis of PGCC in all cases. Even though there was no perioperative mortality,postoperative complications developed in a case were hemorrhage in the early perioperativeperiod and bronchus fistula after two months from the operation. The mean survivalof the patients was estimated as 28.8 months (38 days - 116 months). Conclusion: The main treatment for PGCC is the completesurgical resection. Complete surgical resection was found to be usefull as a treatmentof choice of PGCC in the early stage and contributed to survival.
KW  - Chemotherapy
KW  - giant cell carcinoma
KW  - radiotherapy
KW  - surgery
KW  - World Health Organization
N2  - Amaç: Pulmoner dev hücreli karsinom (PDHK) küçükhücreli dışı akciğer kanserinin bir histolojik tipidir ve akciğer sarkomatoid karsinomununbeş subtipinden biri olarak sınıflandırılır. Pür PDHK çok nadirdir.Gereç ve Yöntem: Kliniğimizde PDHK nedeni ile tedavi gören 7 hastaylailgili tecrübelerimizi sunduk (6 erkek ve 1 kadın, yaş aralığı 46-63 yıl). En sıkgörülen semptomlar öksürük ve hemoptizi idi. Üst lobektomi (n=7) ve ek olarak mediastinallenfadenektomi bütün hastalara uygulandı. Bulgular: Kesin histolojik inceleme ile tüm hastalarda PDHK tanısı doğrulandı.Herhangi bir perioperatif mortalite görülmemesine rağmen bir olguda ameliyat sonrasıkomplikasyon gelişti; erken perioperatif dönemde hemoraji ve operasyondan iki aysonra bronşiyal fistül gelişti. Hastaların ortalama sağkalımı 28,8 ay (38 gün-116ay) olarak bulundu. Sonuç: PDHK için asıl tedavi komplet cerrahi rezeksiyondur. Komplet cerrahirezeksiyonun erken evre PDHK için yararlı bir tedavi tercihi olduğu ve sağkalımakatkı sağladığı bulunmuştur.
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UR  - https://doi.org/10.21601/ortadogutipdergisi.440816
L1  - https://dergipark.org.tr/tr/download/article-file/718828
ER  -