@article{article_447022, title={Antioxidant Safety and Antioxidant-induced Stress}, journal={Kocatepe Veterinary Journal}, volume={11}, pages={491–496}, year={2018}, DOI={10.30607/kvj.447022}, author={Aslan, Recep}, keywords={Antioksidan güvenliği,antioksidatif stres,antioksidanların zararlı etkileri}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:normal;"> <span style="font-size:12pt;font-family:’Times New Roman’, serif;color:#222222;letter-spacing:.2pt;">The safe use
of antioxidants and reliable antioxidant applications are a new and important
area of debate that has been continuing for decades. Today, antioxidant plants,
phytochemicals and products are the most popular supplements. Most of them are
sold without a prescription, even though they are used like a medicine. We know
many scientific reports on the benefits of antioxidants but there are also
studies that question whether antioxidant products have harmful effects. Nowadays
antioxidant safety is the one of the most important medical topics at
oxidant-antioxidant balance and oxidative stress. A physiological balance exists
between oxidants and antioxidants in the organism only when both of the forces are
present. Studies which document that antioxidant supplementation, inhibits the reactions
and effects of free radicals are common. But, it is still unclear which exogen
antioxidants and doses should be used to have an efective defense and also what
safe limit is for use. It is possible that many of antioxidant phytochemicals
and supplements can cause harmful changes in tissues by initiating different
mechanisms. The most important question related to the use of antioxidants and
antioxidant safety is the names, amounts, kinds and forms of them. The term
antioxidative stress is a new strategic word on oxidant-antioxidant balance as
like as oxidative stress. Antioxidants may cause stress in tisssues which
refers to antioxidative stress. An extraordinary attention on antioxidative
stress is a necessity for today’s medical disciplines. The further studies are
needed to clarify the harmful effects of antioxidants and antioxidative stress
for the antioxidant safety. We aimed to focuse on the antioxidant-induced
stress. For this reason, some reports on the harmful effects of antioxidants have
been discussed in this paper. </span> </p> <p> </p>}, number={4}, publisher={Afyon Kocatepe Üniversitesi}