TY  - JOUR
T1  - Tip II Diyabetes Mellituslu Hastalarda Serum Ürik Asit Ve Gama Glutamil Transferaz Düzeyleri İle Koroner Arter Hastalığı Gelişimi Arasındaki İlişki
TT  - The Relationship Between Type 2 DM Patients With Serum Uric Acid And Gamma Glutamyl Transferase Levels and Development Coronary Artery Disease
AU  - Aksu, Ekrem
AU  - Avcı, Deniz
AU  - Çıkım, Gürkan
AU  - Çelik, Yunus
PY  - 2016
DA  - December
Y2  - 2016
JF  - Harran Üniversitesi Tıp Fakültesi Dergisi
PB  - Harran Üniversitesi
WT  - DergiPark
SN  - 1304-9623
SP  - 231
EP  - 236
VL  - 13
IS  - 3
LA  - tr
AB  - Amaç: Çalışmamızda koroner arter hastalığının (KAH) eşlik ettiği tip 2 diyabetesmellituslu (DM) hastalarlatip 2 DM tanısıyla takip edilen hastalar serum ürik asit (SÜA) ve gama glutamiltransferaz (GGT) düzeyleridiğer metabolik parametreler ile birlikte incelenerek prospektif olarak karşılaştırılmış; diyabetik hastalardabu parametreler ile KAH gelişimi arasındaki ilişki ortaya koymak amaçlanmıştır.Gereç ve Yöntem: Kahramanmaraş Necip Fazıl Şehir Hastanesi\'nde gerçekleştirilen bu çalışmaya,kardiyoloji polikliniğine başvuran tip II DM'lI 118 hasta, KAH\'nın eşlik ettiği 222 adet tip 2 DM\'li hastadahil edildi.Bulgular: Guruplar arasında SÜA düzeylerinde anlamlı farkın olmadığı (5.37±1.48 vs 5.27±1.51 mg/dl;p=0.194), GGT düzeyinin ise tip II DM'nin eşlik ettiği KAH olan grupta sadece tip II DM olan gruba göreistatistiki olarak anlamlı olarak daha yüksek olduğunu tespit ettik(23,0 (16,0-32,50) vs 25 (18,0-39,0) U/L; P< 0,0001).Sonuç: Çalışmamızda serum GGTdüzeyinin diyabetli hastalarda kardiyovasküler riskin artışını gösteren birprediktör olabileceğini gözlemledik. Ancak SÜAseviyesiyle tip II DM'li hastalarda KAH riski arasında ilişkisaptanamamıştır
KW  - Ürik Asid
KW  - Gama glutamil Transferaz
KW  - Tip II Diyabetes Mellitus
KW  - Koroner Arter Hastalığı
N2  - Objective: In this study we prospectively compared the patients with coronary artery disease (CAD)accompanied type 2 diabetes mellitus (DM) and patients followed with type 2 diabetes in view of the serumuric acid (SUA) and glutamil gamma transferase (GGT) levels furthermore metabolic parameters; it istargeted to reveal the relationship between these parameters and CAD development risk in diabetic patients.Materials-Methods: 118 patients with type ll DM and 222 type 2 DM patients with CAD who were appliedto the cardiology output clinic enrolled to the study.Results: No significant difference was established between groups for SUAlevels (5.37 ± 1,48 vs 5.27±1,51mg/dl; p=0,194) , while the GGT levels in CAD with type ll DM detected statistically significent higher than type II DM group(23.0 (16,0-32,50) vs 25 (18,0-39,0)U/L; P< 0,001).Conclusion: We observed serum GGTlevels in DM patients are a predictor of the raising cardiovascular risk.However, SUAlevels in type II DM are not have a relation with the risk of CAD.
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UR  - http://dergipark.org.tr/tr/pub/hutfd/issue//447081
L1  - http://dergipark.org.tr/tr/download/article-file/512281
ER  -