TY  - JOUR
T1  - Postnatal 38.Günde Oral Parasetamol Tedavisiyle Kapanan Hemodinamik Anlamlı Patent Duktus Arteriosus Olgusu
TT  - A Hemodynamically Significant Patent Ductus Arteriosus Case which was Closed at 38th Day with Oral Paracetamol Therapy
AU  - Akar, Selahattin
AU  - Almaz, Veysi
AU  - Turgut, Mehmet
PY  - 2019
DA  - September
DO  - 10.16948/zktipb.447404
JF  - Zeynep Kamil Tıp Bülteni
PB  - Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH
WT  - DergiPark
SN  - 1300-7971
SP  - 156
EP  - 158
VL  - 50
IS  - 3
LA  - tr
AB  - Patent duktus arteriosus özellikle küçükprematürelerin önemli sorunlarından biridir. 25 gebelik haftasında 515 grağırlığında doğan prematüre bebek yenidoğan servisine yatırıldı.Respiratuvardistres sendromu (RDS) nedeniyle iki kezsurfaktan tedavisi uygulanan hastanın postnatal 25.günde hemodinamik anlamlı patentduktus arteriosus (PDA) saptanması nedeniyle hastaya 2 kür oral ibuprofentedavisi verildi.İbuprofen sonrası duktusu kapanan hastanın postnatal 38.günde klinikve laboratuvar olarak sepsis gelişen hastanın ekokardiyografisinde(EKO)duktusunun açıldığı ve hemodinamikanlamlı olduğu saptandı. Trombositopenisiolması nedeniyle hastaya medikal kapatma tedavisi olarak oral parasetamol başlandı.Oral parasetamol tedavisi sonrasıkontrol EKO’sunda PDA’nın kapandığı görüldü.Klinik izleminde hastanın genel durumu iyi seyretti.Postnatal 110.günde 2120 gramaulaşan hasta yenidoğan polikliniğine kontrole gelmek üzere taburcu edildi.Sonuçolarak ibuprofen tedavisine yanıt vermeyen ya da ibuprofen tedavisininkontrendike olduğu durumlarda geç dönemde de parasetamol tedavisi alternatifseçenek olabilir.
KW  - prematüre
KW  - oral parasetamol
N2  - Patentductus arteriosus is one of the important problem in premature infants. Apremature infant weighed 515 g at 25th week of gestation was admitted in theneonatal intensive care unit. The patient administered surfactant therapy two timesfor respiratory distress syndrome (RDS) was given 2 cure of oral ibuprofentherapy due to hemodynamically significant patent ductus arteriosus (PDA)detected. Echocardiography of the patient whom ductus was closed afteribuprofen therapy and who clinically and laboratorially developed sepsis at the38th postnatal day revealed that the ductus was hemodynamically significantlyopen. Upon the patient had thrombocytopenia, oral paracetamol therapy wasinitiated as medical closure treatment. After the treatment, control ECHOshowed a closed PDA. General status of the patient was normal during thefollow-up. The patient reached to 2,120 g at the 110th postnatal day, and wasdischarged to home with outpatient clinic control plan. In conclusion,paracetamol treatment may be an alternative option also in late periods in thecases of unresponsiveness to ibuprofen or a contraindication for thisagent.
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UR  - https://doi.org/10.16948/zktipb.447404
L1  - https://dergipark.org.tr/tr/download/article-file/834150
ER  -