TY - JOUR T1 - Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome): Case Report TT - Polianjitisle Seyreden Eozinofilik Granülomatozis (Churg Strauss Sendromu): Olgu Sunumu AU - Tanrıverdi, Hakan AU - Uygur, Fırat AU - Altınsoy, Bülent AU - Erboy, Fatma AU - Yazgan, Ömer AU - Atalay, Figen PY - 2016 DA - April Y2 - 2015 JF - Harran Üniversitesi Tıp Fakültesi Dergisi PB - Harran Üniversitesi WT - DergiPark SN - 1304-9623 SP - 84 EP - 87 VL - 13 IS - 1 LA - en AB - Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotizing vasculitis characterized bytissue and blood eosinophilia. Several drugs including leukotriene receptor antagonists (LTRAs) aresuspected to trigger EGPAdevelopment. Here, we present a case of EGPAunrelated to LTRAs. KW - Eosinophilia KW - Leukotriene Receptor Antagonists KW - Eosinophilic Granulomatous KW - Vasculitis N2 - Polianjitisle birlikte seyreden eozinofilik granülomatozis (Churg Strauss sendromu), nadir, sıklıkla solunumsistemini tutan ve özellikle küçük ve orta çaplı damarları etkileyen, astım ve doku eozinofilisi ile karakterize,sistemik nekrotizan bir vaskülittir. Lökotrien antagonistlerini de içeren pek çok ilacın bu hastalığıngelişiminde rolü olduğundan şüphelenilmektedir. Biz de klinik ve radyolojik bulgularla tanı alan ve lökotrienreseptör antagonistleri ile ilişkili olmadığını düşündüğümüz bir olguyu sunmak istedik.  CR - 1.Groh M, Pagnoux C, Baldini C, Bel E, Bottero P, Cottin V et al. Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management. Eur J Intern Med. 2015;26 (7):545-53. http://dx.doi.org/10.1016/j.ejim.2015.04.022 CR - 2.Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P, Stern M et al. Long-term outcomes of 118 patients with eosinophilic granulomatosis with polyangiitis (ChurgStrauss syndrome) enrolled in two prospective trials. J Autoimmun 2013;43:60-9. CR - 3.Ramentol-Sintas M, Martínez-Valle F, Solans-Laqué R. Churg–Strauss Syndrome: An evolving paradigm. Autoimmun Rev 2012;12(2):235–40. Masi AT 1 CR - 4. , Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum. 1990;33(8):1094-100. CR - 5.Yıldız F, Zorludemir S, Erken E. Montelukast ilişkili Churg Strauss sendromu: Üç olgu. Cukurova Med J 2014;39(2):347-52 CR - 6.Bibby S, Healy B, Steele R, Kumareswaran K, Nelson H, Beasley R. Association between leukotriene receptor antagonist therapy and Churg–Strauss syndrome: an analysis of the FDA AERS database. Thorax 2010;65(2):132–8 CR - 7.Hauser T, Mahr A, Metzler C, Coste J, Sommerstein R, Gross WL, e t a l. The l eucotri ene r e c eptor antagonistmontelukast and the risk of Churg–Strauss Sy n d r ome : a c a s e - c r o ss o v e r st u d y. Th o r a x 2008;63(8):677–82. CR - 8.Abril A, Calamia KT, Cohen MD. The Churg Strauss syndrome (Allergic granulomatous angiitis): Review and update. Semin Arthritis Rheum 2003;33:106-14. UR - https://dergipark.org.tr/tr/pub/hutfd/issue//447547 L1 - https://dergipark.org.tr/tr/download/article-file/513175 ER -