@article{article_458846, title={Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients}, journal={Ege Tıp Dergisi}, volume={58}, pages={126–130}, year={2019}, DOI={10.19161/etd.458846}, url={https://izlik.org/JA85RC36WP}, author={Kılıç, Korhan and Derman, Eylül and Sakat, Muhammed Sedat and Gözeler, Mustafa Sıtkı and Uslu, Hakan and Şengöz, Furkan}, keywords={Hemodiyaliz,dış kulak yolu,nazal kavite,immün süpresyon,antimikrabiyal duyarlılık.}, abstract={<p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Aim: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">The effect of normal
bacterial flora on the immune system is to make it more effective against
harmful micro-organisms and to maintain it in readiness for a more rapid
response. <b> </b> </span> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">The purpose of this study was to
determine the bacterial flora in the external ear canal and nasal cavities in
hemodialysis patients, to compare this with the normal population and to show
the microorganisms’ antibiotic susceptibilities. </span> </p> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Materials
and Methods: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Patients receiving hemodialysis
therapy for at least 3 years were included in the study. A control group (n=62)
was established consisting of patients with no immune-suppressive condition and
presenting to hospital with non-ear symptoms. Swab specimens were taken from
all subjects’ external ear canals and nasal cavities. Results of the cultures
were recorded and antimicrobial susceptibility test was performed. </span> </p> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Results: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> The most commonly isolated micro-organisms in the study group were
MRCoNS (41%), followed by MSCoNS (15.5%) and diphtheroids (9.8%). The
micro-organism most commonly isolated from the nasal cavity in the study group
was CoNS (52.7%), of which MRCoNS constituted 69.2%. <b> </b> </span> </p> <p> <b> </b> </p> <b> </b> <p> </p> <p class="MsoNormal" style="margin-top:2pt;margin-right:0cm;margin-bottom:3pt;margin-left:0cm;text-align:justify;line-height:12.1pt;"> <b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Conclusion: </span> </b> <span lang="en-us" style="font-size:9pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">We think that infections that play a major role in
mortality and morbidity in hemodialysis patients may originate from the
external ear canal as much as the nasal cavity, for this reason it is important
for micro-organisms colonizing these regions to be eliminated with appropriate
treatment on the basis of antibiotic susceptibility tests.  </span> </p> <p> </p>}, number={2}