@article{article_474694, title={Ciprofloxacin is not a better choice in the patients with diabetes suffering urinary tract infection}, journal={Dicle Medical Journal}, volume={46}, pages={65–72}, year={2019}, DOI={10.5798/dicletip.474694}, author={Ugur, Kader and Bal, İsa Ahmet and Tartar, Ayse Sagmak and Gozel, Nevzat and Orhan, Bedrettin and Donder, Emir and Ozercan, Abdullah Mubin}, keywords={Diabetes mellitus,urinary tract infection}, abstract={<p class="MsoNormal"> <span lang="en-us" xml:lang="en-us">Objective:
The aim of this study is to determine antibacterial susceptibilities of
Gram-negative bacteria isolated from diabetic and non-diabetic patients as
infectious agents of community-acquired urinary tract infections (UTI) and to
compare their rates of resistance to the antibiotics frequently used in
empirical treatment. </span> </p> <p> </p> <p class="MsoNormal"> <span lang="en-us" xml:lang="en-us">Methods:
Ninety-six diabetic and sixty-eight non-diabetic (total n=164) patients’ data
were evaluated retrospectively who diagnosed as community-acquired urinary
system infection and consulted to outpatient clinics of Department of
Endocrinology and Infectious Diseases of Firat University School of Medicine
between January 1st , 2014 and December 31st, 2014 whose urine cultures
demonstrated Gram-negative bacteria were included in the study. Antibiotic
susceptibilities of the isolated bacteria were determined using Vitek 2
automated system and the results were evaluated as sensitive and resistant. </span> </p> <p> </p> <p class="MsoNormal"> <span lang="en-us" xml:lang="en-us">Results: In
both diabetic and non-diabetic patient groups, most frequently Escherichia coli
(88.5% in diabetic and 85.3% in non-diabetic groups) were isolated. In the
diabetic group, microorganisms mostly demonstrated the highest rates of
resistance against ampicillin, cephalosporins, ciprofloxacin,
amoxicillin-clavulanic acid and in the non-diabetic group ampicillin,
amoxicillin-clavulanic acid, cefuroxime and trimethoprim-sulfamethoxazole. </span> </p> <p> </p> <p class="MsoNormal"> <span lang="en-us" xml:lang="en-us">Conclusion:
Resistance to ciprofloxacin was at a significantly higher rate in the diabetic
group. In diabetic patients, it will be more appropriate to give antibiotherapy
in urinary system infections based on the antibacterial susceptibility test
results. </span> </p>}, number={1}, publisher={Dicle Üniversitesi}