TY - JOUR T1 - ARC (Apiceutical Research Centre): Exploring a New Generation of Medicines from the Beehive AU - Fearnley, James PY - 2018 DA - December JF - Journal of Apitherapy and Nature JO - J.Apit.Nat. PB - Oktay YILDIZ WT - DergiPark SN - 2667-4734 SP - 1 EP - 1 VL - 1 IS - 3 LA - en AB - Modernpharmaceutical medicine is in crisis. The search for the magic bullet isproving ever more elusive and inadequate. Whilst the economically drivenpharmaceutical juggernaut trundle on, the definition and meaning of medicine isbeing redefined – from targeted, synthetic and single molecule to natural,synergistic and holistic. Science is turning back again to natural wholeproducts with a new will to understand their complexity, intricacy and potencyas medicines for man. Medicines from the beehive as with plant medicines havebeen used for millennia. In our short sightedness however, we have isolated theloudest instruments in the orchestra and synthesised them, but we have lost thesymphony.             Wemust thank the East Europeans for keeping alive a scientific understanding ofbee medicines. Over 40 years ago the Kazan Veterinary Institute publishedresearch which showed that combining propolis with antibiotics increased theeffectiveness of the antibiotics by up to 100 times. We had to wait till the1990’s before the West began to publish scientific papers. Thanks to abrilliant combination of marketing and science, Manuka Honey has become knownto millions of consumers worldwide as a natural antibiotic. It is a shame thatthis marketing drive has left those same consumers thinking only Manuka honeyhas antibiotic properties. Research into propolis, potentially the greatestmedicinal jewel in the beehive treasure chest, has grown exponentially over thelast ten years with Brazil, China, Turkey and India now major contributors.             Researchin UK has grown steadily over the last 15 years particularly at the universityof Strathclyde in Scotland. They have developed a greater understanding of howthe chemical compounds collected by the honey bee from plants and trees withintheir local environment is transformed by the honey bee into a product able toprovide immune defence for the whole superorganism which is the bee colony.             Therelationship between climate and the antibacterial properties of propolis isnow more clearly understood. The discovery of anti-trypanosome chemicals inpropolis in areas where there is sleeping sickness has opened exciting newresearch possibility.ARC (Apiceutical Research Centre) foundedin 2010 has grown out of these insights, in particular the concept that the beehive could be a source of a unique new generation of (Geographic) Medicines forman.             Since2011 ARC has been linking research activity round the world through a series ofinternational conferences and more recently through the formation of IPRG(International Propolis Research Group). ARC’s Global BeePharma project furtherexplores the concept of Geographic Medicine i.e. valuable therapeutics for manderived from the unique transformation by the honey bee of the plants defencemechanism (generated in response to its environment), into the honey beesimmune support mechanism and the positive relationship of these immune defenceproducts to the diseases effecting man in those same geographic areas. ARC hasdeveloped plans to build The BeeArc, a physical research centre and exhibitioncentre based in North Yorkshire UK and focussed on Apiceuticals – medicinesfrom the beehive and sustainable beekeeping.  KW - Beehive KW - Propolis CR - . UR - https://dergipark.org.tr/tr/pub/jan/issue//488463 L1 - https://dergipark.org.tr/tr/download/article-file/582544 ER -