TY  - JOUR
T1  - Correlation Between Chemical Composition and Antibacterial Activity of Propolis from Different Locations in Transilvania
AU  - Bobıs, Otilia
AU  - Domokos, Erzsébet-timea
AU  - Urcan, Adriana
AU  - Margıtas, Liviu Alexandru
AU  - Dezmırean, Daniel Severus
PY  - 2018
DA  - December
JF  - Journal of Apitherapy and Nature
JO  - J.Apit.Nat.
PB  - Oktay YILDIZ
WT  - DergiPark
SN  - 2667-4734
SP  - 81
EP  - 81
VL  - 1
IS  - 3
LA  - en
AB  - Propolis is aresinous substance collected by honeybees from buds and leaves of trees andplants, mixing with pollen as well as enzymes secreted by bees. It is used bybees as a glue, general-purpose sealer, and draught extruder for beehives.Propolis contains a wide variability ofactive principles (flavonoids and phenolic acids). Variations in the chemicalcomposition of propolis are mainly assigned to the difference in the preferredregional plants visited by honeybees. Flavonoid and esters of phenolic acidsare generally regarded to be responsible for the antimicrobial activity ofpropolis.The aim of the present study was toinvestigate the antibacterial activity of propolis samples collected from 5counties in Transylvania (Romania) against different bacterial strains: threeGram-positive bacteria (Staphylococcusaureus, Bacillus cereus, Listeria monocytogenes), twoGram-negative bacteria (Escherichia coli,Pseudomonas aeruginosa) and, alsodifferent bacteria responsible for different bee diseases. The methodology usedfor the determination was agar diffusion technique. Enroxil was used aspositive control and alcohol as negative control.  The tested ethanolic propolis extracts are richsources of polyphenolic substances (high amounts of phenolic acids andflavonoids were quantified in the samples) and show a good antibacterialactivity against Gram-positive bacteria. As for the Gram-negative bacteria theresults obtained are very different. It can be concluded that a positivecorrelation exists between antibacterial activity and the content ofpolyphenols and, also between antibacterial activity of extracts and somespecific compounds from propolis. 
KW  - Chemical Composition
KW  - Antibacterial Activity
KW  - Propolis
CR  - .
UR  - https://dergipark.org.tr/tr/pub/jan/issue//490187
L1  - https://dergipark.org.tr/tr/download/article-file/585209
ER  -