TY  - JOUR
T1  - An Analysis of the Pharmacological Components of Herbal Teas Used for Galactagogue Effects by Gas Chromatography/Mass Spectrometry.
TT  - Galaktagog Etki İçin Kullanılan Bitkisel Çayların Farmakolojik Bileşenlerinin Gaz Kromatografisi/ Kütle Spektrometrisi ile Analizi
AU  - Ulusoy, Kemal Gökhan
AU  - Özdoğan, Fidan Pesen
AU  - Arslan, Seyfullah Oktay
AU  - Macit, Enis
AU  - Çam, Saliha Ayşenur
AU  - Uysal, Fatma
AU  - Doğan, Muhammed Fatih
PY  - 2019
DA  - June
Y2  - 2019
DO  - 10.21673/anadoluklin.494566
JF  - Anatolian Clinic the Journal of Medical Sciences
JO  - Anatolian Clin
PB  - Hayat Sağlık ve Sosyal Hizmetler Vakfı
WT  - DergiPark
SN  - 2149-5254
SP  - 101
EP  - 114
VL  - 24
IS  - 2
LA  - en
AB  - Aims: Thepresent study was designed to detect the phytochemical components of herbs andherbal teas that are used to improve maternal milk production by gaschromatography/mass spectrometry (GC/MS).Methods: Themethanolic extracts were extracted by maceration method using rotaryevaporator. The essential oils of herbs were obtained by Clevenger method.Results: TheGC/MS analysis of the essential oils or the methanol extracts of the mix of herbalteas or herbs including Foeniculumvulgare, Pimpinella anisum, Trigonella foenum graceum, Urtica dioica, Nigella sativa were listed as several compounds in this article.Furthermore, the possible pharmacological effects of these components have beendiscussed according to the literature.Conclusions: Thefindings of this study will guide researchers about the pharmacological activeingredients of these herbs and herbal teas that may be used in the future formilk enhancing or other medical purposes.
KW  - Milk-increasing herbal teas
KW  - Foeniculum vulgare
KW  - Pimpenella anisum
KW  - Trigonella foenum graceum
KW  - Urtica diotica
KW  - Nigella Sativa
N2  - Amaç:Bu çalışmada, anne süt üretimini arttırmak için kullanılan bitki ve bitkiselçayların bileşenlerinin gaz kromatografisi/kütle spektrometresi (GC/MS) ilesaptanması amaçlanmıştır.Gereç ve Yöntemler:Metanolikekstraksiyonlar, maserasyon metodu ve rotary buharlaştırıcıkullanılarak hazırlanmıştır. Uçucu yağların elde edilmesinde ise Clavengeryöntemi kullanılmıştır.Bulgular:Foeniculum vulgare, Pimpenella anisum,Trigonella foenum graceum, Urtica dioica, Nigella Sativa tıbbi bitkilerininve bunların karışım çaylarının uçucu yağları ve methanol ekstraksiyonlarınınGC/MS analizleri yüksek hassasiyetle gerçekleştirilmiştir. Analizlerde tespitedilen kimyasal bileşenler ayrıntılı olarak tablolarda belirtilmiştir. Ayrıcabu bileşenlerin olası farmakolojik etkileri literatür ışığında yorumlanmıştır.Sonuç:Bu araştırmanın bulguları, gelecekte süt arttırıcı veya diğer tıbbi amaçlarlakullanılabilecek bu bitki ve bitkisel çayların farmakolojik aktif bileşenleriüzerine yapılacak araştırmalarda yol gösterici olacaktır.
CR  - 1.  Tabares FP, Jaramillo JVB, Ruiz-Cortés ZT. Pharmacological overview of galactogogues. Vet Med Int.  2014;2014:602894. Doi: 10.1155/2014/6028942.Turkyılmaz C, Onal E, Hirfanoglu IM, Turan O, Koç E, Ergenekon E, Atalay Y. The effect of galactagogue herbal tea on breast milk production and short-term catch-up of birth weight in the first week of life. J Altern Complement Med. 2011 Feb;17(2):139-42. Doi: 10.1089/acm.2010.00903. Rather MA, Dar BA, Sofi SN, Bhat BA, Qurishi MA. Foeniculum vulgare: A comprehensive review of its traditional use, phytochemistry, pharmacology, and safety. Arab J Chem. 2012; 9(Supplement 2):1574–1583. Doi:10.1016/j.arabjc.2012.04.0114. Badgujar SB, Patel VV, Bandivdekar AH. Foeniculum vulgare Mill: A review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology. Biomed Res Int. 2014;2014:842674. Doi: 10.1155/2014/842674.5. Koriem KMM. Approach to pharmacological and clinical applications of Anisi aetheroleum.Asian Pac J Trop Biomed.2015; 5(1):60–67.Doi: 10.1016/S2221-1691(15)30172-66. Moniruzzaman, Shahinuzzaman, Haque A, Khatun R, Yaakob Z. Gas chromatography mass spectrometry analysis and in vitro antibacterial activity of essential oil from Trigonella foenum-graecum. Asian Pac J Trop Biomed. 2015; 5(12): 1033-1036. Doi:10.1016/j.apjtb.2015.09.0107. Kıralan M, Yorulmaz A, Çalıkoğlu E, Bayrak A. Çemen otu (Trigonellafoenum-graecum L.) tohumunun yağ asitleri ve sterol bileşimi. Derim, 2017; 34(2):138-14. Doi: 10.16882/derim.2017.2849828. Wani SA, Kumar P. Fenugreek: A review on its nutraceutical properties and utilization in various food products. J Saudi Soc Agric Sci. 2017; 17(2): 97–106. Doi: 10.1016/j.jssas.2016.01.0079. Bahmani M, Shirzad H, Mirhosseini M, Mesripour A, Rafieian-Kopaei M. A Review on Ethnobotanical and Therapeutic Uses of Fenugreek (Trigonellafoenum-graceum L). J Evid Based Complementary Altern Med. 2016;21(1):53-62. Doi: 10.1177/2156587215583405. 10. Al-Asadi JN. Therapeuticuses of Fenugreek (Trigonellafoencum-graecum L.).Am J Soc Issues Humanit. 2004;3(1):21–36.11. Hosseinzadeh H, Tafaghodi M, Mosavi MJ, Taghiabadi E. Effect of aqueous and ethanolic extracts of Nigella sativa seeds on milk production in rats. J Acupunct Meridian Stud. 2013;6(1):18-23. Doi: 10.1016/j.jams.2012.07.019.12.  Gaya BI, Maje MI, Emmanuel SN, Muhammad UA. Lactogenic Study of The Crude Extract of Nigella Sativa Seed on Serum Prolactin Level of Lactating Albino Rats. Niger J Sci Res. 2015:14(2):85–89.13. Jalili C, Salahshoor MR, Yousefi D, Khazaei M, Shabanizadeh Darehdori A, Mokhtari T. Morphometric and Hormonal study of the effect of Utrica diocia Extract on Mammary Glands in Rats. Int J Morphol. 2015;33(3):983-987.14. Westfall RE. Galactagogue Herbs: A Qualitative study and Review. Can J Midwifery Res Pract. 2000; 2(2):22–27.15. Abascal K, Yarnell E. Botanical Galactagogues. Altern Complement Ther. 2008;14(6):288–294.16. Özcan MM, Chalchat JC. Chemical composition and antifungal effect of anise (Pimpinella anisum L.) fruit oil at ripening stage. Ann Microbiol. 2006;56(4):353–358.17. Hadi MY, Mohammed GJ, Hameed IH. Analysis of bioactive chemical compounds of Nigella sativa using gas chromatography-mass spectrometry. J Pharmacognosy Phytother. 2016,8(2):8–24. Doi:10.5897/JPP2015.036418. Rathore SS, Saxena SN, Kakani RK, Sharma LK, Agrawal D, Singh B.Genetic variation in fatty acid composition of fenugreek (Trigonella foenum-graecum L .) seed oil. Legume Research. 2017;40(4):609-617. 19. Singh O, Khanam Z, Misra N, Srivastava MK. Chamomile (Matricaria chamomilla L.): An overview. Pharmacogn Rev. 2011;5(9):82-95. Doi: 10.4103/0973-7847.79103.20. Fitsiou E, Mitropoulou G, Spyridopoulou K, Tiptiri-Kourpeti A, Vamvakias M, Bardouki H, Panayiotidis MΙ, Galanis A, Kourkoutas Y, Chlichlia K, Pappa A. Phytochemical Profile and Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum and Fortunella margarita. Molecules. 2016; 21(8: E1069. Doi: 10.3390/molecules2108106921. Skalicka-Woźniak K, Walasek M, Ludwiczuk A, Głowniak K. Isolation of terpenoids  from Pimpinella anisum essential oil by high-performance counter-current chromatography. J Sep Sci. 2013;36(16):2611-2614. Doi: 10.1002/jssc.201300407.22. Arslan N, Gürbüz B, Sarihan EO. Variation in essential oil content and composition in Turkish anise (Pimpinella anisum l .) populations. Turk J Agric For. 2004;28(3):173–177. 23. Bano, Tabassum H, Ahmad A, Mabood A, Ahmad IZ. The medicinal significance of the bioactive compounds of Trigonella Foenum-Graecum: a review. Int J Res Ayurveda Pharm. 2016;7(4):84–91.24. Joshi BC, Mukhija M, Kalia AN. Pharmacognostical review of Urtica dioica L. J Green Pharm. 2014;8(4):201–209. 25. Burits M, Bucar F. Antioxidant activity of Nigella sativa essential oil. Pytotherapy Res. 2000;14(5):323–328. 26. Joshi M, Nair S. HPLC analysıs of Trigonella Foenum-Graecum seeds to assess phytoestrogens. Int J Food Nutr Sci. 2014;3(1):61–64. 27. Dhouibi R, Moalla D, Ksouda K, Ben Salem M, Hammami S, Sahnoun Z, Zeghal KM, Affes H. Screening of analgesic activity of Tunisian Urtica dioica and analysis of its major bioactive compounds by GC/MS. Arch Physiol Biochem. 2017;20:1-9. Doi: 10.1080/13813455.2017.1402352.28. Tabanca N, Demirci B, Ozek T, Kirimer N, Baser KH, Bedir E, Khan IA, Wedge DE. Gas chromatographic-mass spectrometric analysis of essential oils from Pimpinella species gathered from central and northern Turkey. J Chromatogr A. 2006;1117(2):194-205. 29. Calapai G, Delbò M, SilanoV. Assessment report on Pimpinella anisum L.,fructus and Pimpinella anisum L., aetheroleum. Eur Med Agency. 2013;44:1–25.
UR  - https://doi.org/10.21673/anadoluklin.494566
L1  - https://dergipark.org.tr/tr/download/article-file/736022
ER  -