@article{article_496711, title={Age-related Changes in the Left Ventricular Twist}, journal={Koşuyolu Heart Journal}, volume={20}, pages={125–129}, year={2017}, author={Yılmaz, Sabiye and Kılıç, Harun and Demirtaş, Saadet and Vatan, Mehmet Bülent and Edem, Efe and Ağaç, Mustafa Tarık and Türker Pabuccu, Mustafa and Çakar, Mehmet Akif and Vural, Mustafa Gökhan and Aksoy, Murat and et al.}, keywords={Ekokardiyografi,rotasyon ve büküm,yaşlanma}, abstract={ Introduction: Left ventricular (LV) rotation and twist play important roles in LV contraction and relaxation. Systolic function is usually preserved with aging, but diastolic function deteriorates. The aim of this study was to establish a reference value for LV twist and examine the effect of aging on it. <o:p> </o:p> Patients and Methods: We enrolled 75 healthy subjects who were divided into two groups according to age: < 40 and > 40 years. LV rotation and twist were assessed with two-dimensional speckle tracking imaging at the basal and apical levels of the parasternal short axis. LV twist was defined as an apical rotation relative to the baseline. Exclusion criteria included a history of ischemic and valvular disease, arrhythmia, use of a pacemaker, and systolic dysfunction. <o:p> </o:p> Results: Peak A wave velocity (70.6 ± 13.7 vs. 57.7 ± 10.6, p< 0.001) and E/E’ratio (7.7 ± 2.2 vs. 6.1 ± 1.3, p< 0.001) were higher and peak E wave velocity (52.4 ± 16 vs. 76.8 ± 11, p< 0.001) and E/A ratio (0.75 vs. 1.34, p< 0.001) were lower in old patients than in young patients. There was an increase in apical rotation (4.4 ± 2.9° vs. 3.3 ± 2.4°, p= 0.075) and a decrease in basal rotation (−4.1 ± 2.7° vs. −5.2 ± 3.7°, p= 0.185) in old patients, but these changes indicated no significant difference. With aging, the twist increased (8.6 ± 3.3° vs. 8.5 ± 4.1°, p= 0.890), but not significantly. LV apical rotation (5 ± 3.2 vs. 2.4 ± 1.1, p= 0.004) and twist (9.4 ± 3.4 vs. 6.9 ± 2.4, p= 0.64) decreased in the old group with an increasing degree of LV diastolic dysfunction. <o:p> </o:p> <span style="font-size:10.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family: "MS Mincho";mso-fareast-theme-font:minor-fareast;mso-ansi-language:TR; mso-fareast-language:EN-US;mso-bidi-language:AR-SA">Conclusion: <span style="font-size:10.0pt;font-family:"Arial","sans-serif";mso-fareast-font-family: "MS Mincho";mso-fareast-theme-font:minor-fareast;mso-ansi-language:TR; mso-fareast-language:EN-US;mso-bidi-language:AR-SA"> LV twist slightly increased with age, but this effect was reversed with increased diastolic dysfunction even in the presence of normal systolic function. }, number={2}, publisher={Kartal Koşuyolu Yüksek İhtisas EAH}