TY - JOUR T1 - 3D MICROFABRICATION AND MIXING PHENOMENA IN MICROFLUIDICS TT - 3D MICROFABRICATION AND MIXING PHENOMENA IN MICROFLUIDICS AU - Saygılı, Ecem AU - Yeşil Celiktaş, Özlem PY - 2018 DA - November JF - Ejovoc (Electronic Journal of Vocational Colleges) JO - Ejovoc PB - Kırklareli Üniversitesi WT - DergiPark SN - 2146-7684 SP - 175 EP - 177 VL - 8 IS - 2 LA - en AB - Microfluidic devicesare currently replacing their macroscopic counterparts in many applications.Controlling the mass transport in the microchannels mostly depends on materialused and channel geometry is the key parameter to improve flows speed, reactionsensitivity and surface robustness. As the flow type in the microfluidicchannels is laminar, micro-mixers have been using to provide semi-turbulentflow inside the microchannels. In this study, microfluidic molds werefabricated by using 3D printing method and mixing phenomena was observed indifferent microplatforms with and without micro-mixer geometries to understandthe underlying diffusion mechanism, which causes to mixing phenomena in themicrochannel. KW - microfluidics KW - diffusion KW - micromixer N2 - Microfluidic devicesare currently replacing their macroscopic counterparts in many applications.Controlling the mass transport in the microchannels mostly depends on materialused and channel geometry is the key parameter to improve flows speed, reactionsensitivity and surface robustness. As the flow type in the microfluidicchannels is laminar, micro-mixers have been using to provide semi-turbulentflow inside the microchannels. In this study, microfluidic molds werefabricated by using 3D printing method and mixing phenomena was observed indifferent microplatforms with and without micro-mixer geometries to understandthe underlying diffusion mechanism, which causes to mixing phenomena in themicrochannel. CR - Akay, S., Heils, R., Trieu, H. K., Smirnova, I., & Yesil-Celiktas, O. (2017). An injectable alginate-based hydrogel for microfluidic applications. Carbohydrate Polymers, 161, 228–234. https://doi.org/10.1016/j.carbpol.2017.01.004 Bhatia, S. N., & Ingber, D. E. (2014). Microfluidic organs-on-chips. Nature Biotechnology, 32(8), 760–772. https://doi.org/10.1038/nbt.2989 Erkal, J. L., Selimovic, A., Gross, B. C., Lockwood, S. Y., Walton, E. L., McNamara, S., … Spence, D. M. (2014). 3D printed microfluidic devices with integrated versatile and reusable electrodes. Lab on a Chip, 14(12), 2023–2032. https://doi.org/10.1039/c4lc00171k McCreedy, T. (2000). Fabrication techniques and materials commonly used for the production of microreactors and micro total analytical systems. TrAC - Trends in Analytical Chemistry, 19(6), 396–401. https://doi.org/10.1016/S0165-9936(99)00176-4 Ren, K., Chen, Y., & Wu, H. (2014). New materials for microfluidics in biology. Current Opinion in Biotechnology, 25, 78–85. https://doi.org/10.1016/j.copbio.2013.09.004 Saggiomo, V., & Velders, A. H. (2015). Simple 3D Printed Scaffold-Removal Method for the Fabrication of Intricate Microfluidic Devices. Advanced Science, 2(9), 1–5. https://doi.org/10.1002/advs.201500125 Shallan, A. I., Smejkal, P., Corban, M., Guijt, R. M., & Breadmore, M. C. (2014). Cost-effective three-dimensional printing of visibly transparent microchips within minutes. Analytical Chemistry, 86(6), 3124–3130. https://doi.org/10.1021/ac4041857 UR - https://dergipark.org.tr/tr/pub/ejovoc/issue//498008 L1 - https://dergipark.org.tr/tr/download/article-file/598168 ER -