@article{article_499653, title={Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?}, journal={Ankara Medical Journal}, volume={18}, pages={528–536}, year={2018}, DOI={10.17098/amj.499653}, author={Haskoloğlu, Zehra Şule and Altun, Demet}, keywords={Astımlı çocuk,vitamin D düzeyi,çinko düzeyi,klinik bulgular}, abstract={<b> <span lang="en-us" style="font-size:11pt;line-height:115%;font-family:Constantia, serif;" xml:lang="en-us">Objectives </span> </b> <span lang="en-us" style="font-size:11pt;line-height:115%;font-family:Constantia, serif;" xml:lang="en-us">:
It is reported that deficiencies in vitamin D and zinc are associated with
asthma. In this study we aimed to investigate the relationship between clinic
findings of asthmatic children and vitamin D and zinc levels. <br /> <b>Materials and Methods </b>: This
prospective study included a total of 149 asthmatics and 97 healthy children
with an age range of 5 to 17 years. All of the participants were evaluated for
serum levels of 25 -hydroxyvitamin D (25(OH)D) and zinc, dietary habits, the
rate of respiratory tract infections, hospital visits and levels of sunlight
exposure. <br /> <b>Results </b>: Serum vitamin D and zinc
levels in asthmatic children (7.7±5.29 ng/ml), (64±16.3 mcg/dl) were
significantly lower than that in healthy children (12.3±12.87 ng/ml), (69±26.2
mcg/dl) (p< 0.015), respectively. A relationship was detected between the
frequency of infection and vitamin D level’s being <10ng/ml (p < 0.001),
while no relationship was detected between the frequency of infection and zinc
level. No relationship was detected between pulmonary function, nutrition and
the levels of vitamin D and zinc. However, a relationship was detected between
vitamin D levels and exposure to sunlight. <br /> <b>Conclusion </b>: Our results showed that
asthmatic children had lower vitamin D and zinc levels than healthy children.
Very low levels of vitamin D were found to be associated with an increased rate
of infection and required more medication and hospitalization </span>}, number={4}, publisher={Ankara Yıldırım Beyazıt Üniversitesi}