TY - JOUR T1 - Normalisation values for the resonant frequency of the middle ear in rats AU - Çulhaoğlu, Belde AU - Mıdık, Şule AU - Erbek, Selim Sermed AU - Erbek, Seyra PY - 2018 DA - December Y2 - 2018 DO - 10.32448/entupdates.508087 JF - ENT Updates PB - AVES YAYINCILIK WT - DergiPark SN - 2149-7109 SP - 170 EP - 174 VL - 8 IS - 3 LA - en AB - p { margin-bottom: 0.08in; direction: ltr; color: rgb(0, 0, 0); }p.western { font-family: "Cambria", serif; font-size: 12pt; }p.cjk { font-family: "MS Mincho", "MS 明朝", monospace; font-size: 12pt; }p.ctl { font-family: "Cambria", serif; font-size: 12pt; }Objective:In earlier studies, the resonant frequency (RF) of the middle ear hasbeen investigated in a number of different animals. However, no studyhas so far specifically addressed the measurement of RF in rats. Withthis in mind, inour study, multifrequency tympanometry (MFT) was performed on ratsand RF value measurements were taken.The aim was toascertain the normal values for rats used in our universityexperiments and to provide guidance for further research to beundertaken in this area. Materials and Methods: Forthe study, 16 male and 16 female adult Sprague Downey rats (32animals, 64 ears) aged 10 months old and in healthy condition wereused. MFT at 226Hz frequency and above was performed on all the ratsafter they had been anaesthetised. In the first instance tympanogramswere recorded using the 226Hz probe tone, following which MFTmeasurements were performed. RF values for the middle ear weredetermined in the range 200-2000Hz.Results: Formale rats, the mean RF value was 426.56 (± 193.01 Hz), whilst forfemale rats the mean was 496.88 (± 132.55) Hz. When the valuesobtained for the male and female rats were compared, no statisticallysignificant difference was observed between the two groups (p=0.061).Accordingly, the mean RF value for the rats as a whole (obtained for64 ears) was calculated to be 461.7 (± 168.02) Hz.Conclusion: Inthis research, RF values for the middle ear of rats has beendemonstrated to be measurable. However, further research is neededinto the relationship between RF and the characteristics of themiddle ear in rats. KW - multifrequency tympanometry KW - resonant frequency KW - rat KW - normalisation CR - 1. Terkildsen K, Thomsen K. The influence of pressure variations on the impedance of the human ear drum. J Laryngol Otology 1959; 73: 409–418. CR - 2. Holte L. Aging effects in multifrequency tympanometry. Ear Hear 1996; 17:12–18. CR - 3. Iacovou E, Vlastarakos P.V, Ferekidis E, Nikolopoulos T.P. Multi-Frequency Tympanometry: Clinical Applications for the Assesment of the Middle Ear Status. Indian J Otolaryngol Head Neck Surg 2013; 65(3):283–287. CR - 4. Prabhu P, Manandhar S, Nasima Ahmed B. Test-Retest Reliability of the Components of Multi-Frequency Tympanometry. J International Advanced Otology 2017; 13(1): 74-6. CR - 5. Öz I. Meniere hastalığında gliserol testi ile rezonans frekans farklılığının değerlendirilmesi. Başkent Üniversitesi Sağlık Bilimleri Enstitüsü, Yüksek Lisans Tezi.2018. CR - 6. Margolis RH, Van Camp KJ, Wilso RH. Multifrequency tympanometry in normal ears. J. Audiology 1985; 24: 44-53. CR - 7. Lehnhardt E, Laszig R., Praxis der Audiometrie. Stuttgart, Georg Thieme, 2001. CR - 8. Abou-Elhamd KE, Abd-Ellatif AE, Sultan MA. The role of multifrequency tympanometry in otitis media. Saudi Med J. 2006; Vol.27(3): 357-360. CR - 9. Cole LK, Podell M, Kwochka KW. Impedance audiometry measurements in clinically normal dogs. American Journal of Veterinary Research 2000; 61: 442-5. CR - 10. Shanks J, Shelton C. Basic principles and clinical applications of tympanometry. Clin Audioly. 1991; 24: 299-328. CR - 11. Kiessling J. Impedanzaudiometrie in der HNO Fachpraxis. In: HNO Praxis Heute (Ganz H, Schätzle W, editörler). 5–26, Springer-Verlag, New York, 1982. CR - 12. Rosowski J., Outer and Middle Ears. In: Comparatitive Hearing in Mammals (Fay R, Popper A, editör)., s172–237, New York, Springer-Verlag, 1994. CR - 13. Stieve M, Mojallal H, Battmer R.D, Winter M, Lenarz T., Multifrequency tympanometry: Experimental application after implantation of ossicular replacement prosthesis in rabbits. Otology and Neurotology 2007; 28:875Y877. CR - 14. Steinbach E, Vergleichende untersuchungen an gehörknöchelchen und knochentransplantaten beim kaninchen und menschen. Medizinische Fakultät Tübingen Habilitationsschrift 1973; 31–2. CR - 15. Wiley TL, Cruickshanks KJ, Nondahl DM, Tweed TS. Self- reported hearing handicap and audiometric measures in older adults. Journal of the American Academy of Audiology 1999; 10: 173-179. UR - https://doi.org/10.32448/entupdates.508087 L1 - http://dergipark.org.tr/tr/download/article-file/626099 ER -