@article{article_514572, title={A RESEARCH FOR SOME OXAZOLIDINONES TO EVALUATE THEIR ANTIMICROBIAL ACTIVITY}, journal={Journal of Faculty of Pharmacy of Ankara University}, volume={42}, pages={32–37}, year={2018}, author={Kus, Canan and Ugurlu, Ezgi and Altanlar, Nurten}, keywords={antimikrobiyal aktivite,linezolid,oksazolidinon}, abstract={<div> <span style="font-size: 11px;"> <b>Objectives: </b> <i> In this research, antimicrobial activity of some new oxazolidinone derivatives were evaluated against S. aureus ATCC 25923, E. coli ATCC 25922, B. subtilis ATCC 6633, methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate and C. albicans ATCC 10231. </i> </span> </div> <div> <span style="font-size: 11px;"> <b> <br> </b> </span> </div> <div> <span style="font-size: 11px;"> <b>Material and Method: </b> <i> Formerly obtained and published 10 oxazolidinones were tested against antimicrobial activity and this evaluation was carried out in Mueller-Hinton broth and Sabouraud dextrose broth. </i> </span> </div> <div> <span style="font-size: 11px;"> <b> <br> </b> </span> </div> <div> <span style="font-size: 11px;"> <b>Result and Discussion: </b> <i>Compounds E5, and E9 showed antimicrobial activity against both bacteria and fungi with 25 μg/mL and 50 μg/mL, respectively. Our present research and the others have shown that the electro-negativity degree is very important for the biological activity. </i> </span> </div>}, number={3}, publisher={Ankara Üniversitesi}