@article{article_521204, title={Herpes Zoster Infection In Childhood: Prospective Evaluation of 21 Cases}, journal={Harran Üniversitesi Tıp Fakültesi Dergisi}, volume={16}, pages={33–36}, year={2019}, author={Öztürk, Murat and An, İsa and Aksoy, Mustafa}, keywords={Çocukluk çağı,herpes zoster,varisella zoster virüs}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Background: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
Herpes zoster (HZ) is a disease caused by the reactivation of varicella zoster
virus, which remains latent in the dorsal root ganglion. HZ is a rarely seen
disease in childhood. HZ is more common in pediatric patients with
immunosuppressive drug use, immunodeficiency and malignancy. This study
examined the clinical characteristics of children with HZ. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Methods: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
Twenty one pediatric patients admitted to our dermatology clinic between
January 2017 and July 2018 and diagnosed with HZ were evaluated prospectively.
Patients were evaluated in term of age, sex, affected dermatome, history of
previous varicella, varicella vaccine, accompanying disease, complication
development and treatment. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Results: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
Twelve (57.1%) of the 21 pediatric patients with HZ were male and 9 (42.9%)
were female. The mean age of the patients was 10.1 years (6-16 years).  Fourteen (66.6%) patients had thoracic
dermatome involvement, 5 (23.8%) patients had cervical involvement, and 2
(9.5%) patients had lumbar dermatome involvement.  Two patients were receiving systemic
chemotherapy for ALL. In our study 71.4% of patients had a history of varicella
and there was no history of varicella vaccine in any of the patients. None of the
patients developed dissemination and no major complication was observed. </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Conclusion: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
In conclusion, while HZ is also seen in healthy children, children who are
immunosuppressed are more affected. 
Similar to adult disease, thoracic dermatomal involvement is the most
common. Complications such as postherpetic neuralgia due to HZ in healthy
children are rarely seen. </span> </p> <p> </p>}, number={1}, publisher={Harran Üniversitesi}