TY  - JOUR
T1  - Herpes Zoster Infection In Childhood: Prospective Evaluation of 21 Cases
TT  - Çocukluk Çağında Herpes Zoster Enfeksiyonu:21 Olgunun Prospektif Değerlendirilmesi
AU  - An, İsa
AU  - Öztürk, Murat
AU  - Aksoy, Mustafa
PY  - 2019
DA  - March
Y2  - 2019
JF  - Harran Üniversitesi Tıp Fakültesi Dergisi
PB  - Harran Üniversitesi
WT  - DergiPark
SN  - 1304-9623
SP  - 33
EP  - 36
VL  - 16
IS  - 1
LA  - en
AB  - Background:Herpes zoster (HZ) is a disease caused by the reactivation of varicella zostervirus, which remains latent in the dorsal root ganglion. HZ is a rarely seendisease in childhood. HZ is more common in pediatric patients withimmunosuppressive drug use, immunodeficiency and malignancy. This studyexamined the clinical characteristics of children with HZ.Methods:Twenty one pediatric patients admitted to our dermatology clinic betweenJanuary 2017 and July 2018 and diagnosed with HZ were evaluated prospectively.Patients were evaluated in term of age, sex, affected dermatome, history ofprevious varicella, varicella vaccine, accompanying disease, complicationdevelopment and treatment. Results:Twelve (57.1%) of the 21 pediatric patients with HZ were male and 9 (42.9%)were female. The mean age of the patients was 10.1 years (6-16 years). Fourteen (66.6%) patients had thoracicdermatome involvement, 5 (23.8%) patients had cervical involvement, and 2(9.5%) patients had lumbar dermatome involvement. Two patients were receiving systemicchemotherapy for ALL. In our study 71.4% of patients had a history of varicellaand there was no history of varicella vaccine in any of the patients. None of thepatients developed dissemination and no major complication was observed.Conclusion:In conclusion, while HZ is also seen in healthy children, children who areimmunosuppressed are more affected.Similar to adult disease, thoracic dermatomal involvement is the mostcommon. Complications such as postherpetic neuralgia due to HZ in healthychildren are rarely seen.
KW  - Childhood
KW  - Herpes Zoster
KW  - Varicella zoster virus
N2  - Amaç:Herpes zoster(HZ), dorsal kök ganglionunda latentolarak kalan Varicella zoster virüs’ün reaktivasyonu sonucunda gelişen birhastalıktır. HZ çocukluk çağında nadir görülen bir hastalıktır. HZ, çocuklukçağında immünsupresif ilaç kullanımı, immünyetmezlik ve malignite durumlarında daha sık olarakkarşımıza çıkabilir. Bu çalışmada polikliniğimize başvuran HZ tanısı konulançocuk hastaların kliniközellikleri ve eşlik eden hastalıklar incelendi.Materyalve Metot: Hastanemizderi ve zührevi hastalıkları polikliniğine Ocak 2017- Temmuz 2018 tarihleri arasında başvuranve HZ tanısı konulan 18 yaşından küçük 21 hasta prospektif olarakdeğerlendirildi. Hastalar yaş, cinsiyet, tutulan dermatom, geçirilmiş varisellaöyküsü, varicella aşısı öyküsü, eşlikeden hastalıklar, komplikasyon gelişimi ve tedavi açısından değerlendirildi.Bulgular:HZ tanısı konulan 21 çocuk hastanın 12(%57,1)’si erkek, 9 (%42,9)’ u kızidi. Hastaların yaş ortalaması 10,1 yıl(6-16 yaş) olarak saptandı. On dört(%66,6) hastada torakal dermatom tutulurken, 5 (%23,8) hastada servikalve 2 (%9,5) hastada lomber dermatom tutulumu izlendi. İki hasta ALL tanısınedeniyle sistemik kemoterapi almaktaydı.Hastaların hiçbirinde varisellaaşısı olma öyküsü yoktu. Varisella geçirme öyküsü hastaların15(%71,4)’inde vardı. On altı (%76,1)hastaya sistemik antiviral tedavi verildi. Hastalarımızın hiçbirindedisseminasyon gelişmedi. Hastalarda postherpetik nevralji veya majör birkomplikasyon görülmedi.Sonuç: HZ,immünsupresyonu olan çocuk hastalarda sıklıkla görülmesine rağmensağlıklı çocuklarda da görülebilmektedir. Erişkin hastalarabenzer şekilde en sık torakal dermatomtutulumu görülür. Sağlıklı çocuklarda HZ’ ye bağlı postherpetik nevralji gibikomplikasyonlar nadir olarak görülür.
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UR  - https://dergipark.org.tr/tr/pub/hutfd/issue//521204
L1  - https://dergipark.org.tr/tr/download/article-file/677003
ER  -