TY - JOUR TT - RETROSPECTIVE EVALUATION OF THE RATE OF ANTIBIOTIC RESISTANCE OF GRAM NEGATIVE BACILLUS IN 2006 IN MEDICAL INTENSIVE CARE UNIT OF IZMIR CHEST DISEASES HOSPITAL AU - Gündüz, Ayriz AU - Coşkun, Meral AU - Biçmen, Can AU - Şenol, Güneş AU - Çırak, A. Kadri AU - Halilçolar, Hüseyin PY - 2006 DA - December JF - İzmir Göğüs Hastanesi Dergisi JO - İzmir Göğüs Dergisi PB - İzmir Göğüs Hastalıkları Hastanesi WT - DergiPark SN - 1300-4115 SP - 71 EP - 77 VL - 20 IS - 3 KW - Yoğun bakım ünitesi KW - gram negatif bakteri KW - antibiyotik direnci N2 - Intesive care units are the main source of the widespread infections due to resistant microorganisms. Therefore, financial expenses necessary for nosocomial infection control have been increasing day by day. In this study, antibiotic susceptibilities of gram negative bacteria isolated from the hospitalized patients in the intensive care unit (ICU) of our hospital between 1.1.2006 and 31.12.2006 were analyzed retrospectively. Most frequently isolated microorganisms causing infection were Acinetobacter baumanii, Pseudomonas aeruginosa, Klebsiella spp. and Escherichia coli. It seemed that gram negative bacteria isolated from ICU were significantly resistant to all antibiotic groups. Carbepenem, netilmicin and cefaperazone-sulbactam resistance in Acineto-bacter baumanii isolates were 73.4%, 32.8% and 46%, respectively. The most effective antibiotics against Pseudomonas aeruginosa strains were carbapenems, piperacillin-tazobactam, cefaperazone-sulbactam and amikacin. High level of extended spectrum beta-lactamase production was found in gram negative enteric bacteria. Piperacillin-tazobactam, cefoxitin and amikacin were also found as significantly effective against this group of bacteria in addition to carbepenems and cefaperazone-sulbactam CR - intensive care units in Europe. JAMA 1995; 274: 639-45. CR - Clinical and Laboratory Standards Institute. 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Antimicrobial resistance Yazıflma Adresi: Dr. Ayriz GÜNDÜZ CR - Dr. Suat Seren Göğüs Hastalıkları ve Cerrahisi CR - Eğitim ve Arafltırma Hastanesi, CR - Mikrobiyoloji Laboratuvarı CR - Yeniflehir / İZMİR CR - Tel: 0 232 433 33 33 / 2276 @yahoo.com UR - https://dergipark.org.tr/tr/pub/ighd/issue//521974 L1 - https://dergipark.org.tr/tr/download/article-file/641139 ER -