TY  - JOUR
TT  - THE RELATION OF SERUM CA-125 LEVEL MEASUREMENT WITH DISEASE CHARACTERISTICS AND RESPONSE TO TREATMENT
AU  - Kararmaz, Emine
AU  - Erbaycu, Ahmet Emin
AU  - Tekgül, Serpil
AU  - İzmir, Arzu Güler
AU  - Balcı, Günseli
AU  - Özden, Emel Pala
AU  - Kalenci, Dilek
AU  - Katgı, Nuran
AU  - Güçlü, Salih Zeki
PY  - 2010
DA  - October
JF  - İzmir Göğüs Hastanesi Dergisi
JO  - İzmir Göğüs Dergisi
PB  - İzmir Göğüs Hastalıkları Hastanesi
WT  - DergiPark
SN  - 1300-4115
SP  - 71
EP  - 78
VL  - 24
IS  - 2
KW  - Akciğer kanseri
KW  - CA-125
KW  - tümör hücre tipi
KW  - kemoterapi
KW  - radyoterapi
N2  - Tumor markers are used in the following-up of  the treatment, determination of the prognosis  and the tumor's extensive in the body more  than diagnosis of the tumor in the patients with  the lung cancer.  The patients diagnosed lung cancer between  February 2007 and June 2009 were included into  the study. 105 patients with lung cancer and 39  healthy individuals as "control group" were included.  Serum CA-125 levels of the patients with lung  cancer were measured in the determination of  diagnosis, during the 3rd cure of chemotherapy  and at the end of the treatment in the patients  performed chemotherapy; and the CA-125 levels  were measured approximately 1-3 months after  the treatment in patients performed RT or had  operation.  CA-125 levels in the patients with lung cancer  were 101.9 U/ml during the process following the  determination of diagnosis and were 8.5 U/ml (p=0.000) in healthy control group. In patients  progressing after the treatment, serum CA-125  levels were found significantly high (p=0.03). In  the the evaluation of first response and after  treatment in patients with lung cancer, serum  CA-125 levels did not vary according to tumor  cell type, tumor cell subtype and the stage of  the disease.  Serum CA-125 levels in patients with lung cancer is  significantly higher compared to healthy individuals.  This is not associated with the extensive of tumor  and histopathology. High levels measured after  the treatment is associated with the resistance  to treatment.
UR  - http://dergipark.org.tr/tr/pub/ighd/issue//522327
L1  - http://dergipark.org.tr/tr/download/article-file/641668
ER  -