@article{article_523491, title={Pleural empyema and fibrinolytic therapy in children: A single center experience}, journal={Türkiye Çocuk Hastalıkları Dergisi}, volume={14}, pages={28–35}, year={2020}, DOI={10.12956/tchd.523491}, author={Kanık Yüksek, Saliha and Gülhan, Belgin and Özkaya Parlakay, Aslınur and Tezer, Hasan and Bayram Ilıkan, Gülşah and Cinel, Güzin and Öztorun, Can İhsan and Bostancı, Süleyman Arif and Şahin, Vildan Selin and Şenel, Emrah}, keywords={Plevral ampiyem; Çocuklar; Fibrinolitik tedavi}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Objective: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Pleural
empyema (PE) is a serious complication of pneumonia and continues to be an
important problem. Different treatment approaches are remarkable in many reports,
but do not provide strong evidence for ideal treatment. In this study, we aimed
to evaluate our approach to the patients diagnosed as PE, and to demonstrate
the experience of our center in the shadow of the not fully seated treatment approach
in previously published studies. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Material and Methods: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">This
is a retrospective study of 48 patients aged between 1-17 years from January
2011 to December 2016 in one center. Pre-admission status, risks and treatments
of the patients, clinical and laboratory findings on admission, selected
treatment approaches, especially the fibrinolytic therapy, and complications
were evaluated. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Results: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Tube
thoracostomy was performed in 43/48 (89.6%). Patients treated with fibrinolytic
therapy was 22 (45.8%) and the mean dose was 5,18±2,59 (1-9) in total.
Fibrinolytic therapy was significantly higher in PE stage (II) than the other
stages (p = 0.001). Intensive care need was 20.8% (n = 10) while total hospital
stay was 23.58 ± 8.69 (3-47) days.  Thoracotomy/decortication or VATS were
required in five (10.4%) patients. There was no significant relationship
between the operation and fibrinolytic treatment status of patients. The
complication rate was 41.6% in total. <b> </b> </span> </p> <p> <b> </b> </p> <b> </b> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Conclussion: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">The
therapeutic approach to PE in children is not standardized. As a result, each
center seems to prefer to apply its own treatment approach, considering
previous experiences and results, like in our center. </span> </p> <p> </p>}, number={1}, publisher={T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}