@article{article_525717, title={Effectiveness of light emitting diode phototherapy for direct coombs positive newborns}, journal={Harran Üniversitesi Tıp Fakültesi Dergisi}, volume={16}, pages={169–173}, year={2019}, DOI={10.35440/hutfd.525717}, author={Okur, Nilüfer and Büyüktiryaki, Mehmet and Uras, Nurdan and Öncel, Mehmet Yekta and Ertekin, Ömer and Canpolat, Fuat Emre and Oğuz, Şerife Suna}, keywords={Direkt antiglobulin,Hiperbilirubinemi,Yenidoğan,Fototerapi}, abstract={<p class="MsoNoSpacingCxSpFirst" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us">Background: </span> </b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us"> Phototherapy
is the most frequently used treatment when serum bilirubin levels exceed
physiological limits. The direct antiglobulin titer (DAT) test is regarded as
the cornerstone of diagnosis of immune hemolytic disease of the newborn. </span> </p> <p> </p> <p class="MsoNoSpacingCxSpMiddle" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us">Methods: </span> </b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us"> Patients with
hyperbilirubinemia who were born in our hospital and whose gestational age was
over 35 weeks were enrolled. DAT positive and DAT negative patients were
compared in terms of light emitting diode (LED) phototherapy efficacy. </span> </p> <p> </p> <p class="MsoNoSpacingCxSpMiddle" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us">Results: </span> </b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us"> Seventy-seven
cases were DAT-negative and 72 were DAT-positive. No statistically significant
differences were found for the duration of phototherapy and hospitalization
between the DAT-positive and negative groups. In the DAT-positive group, the
phototherapy needs of the patients were determined to occur at an earlier stage
(postnatal age 1.4 day, p<0.05), and the rate of patients requiring exchange
transfusion, blood transfusion and intravenous immunoglobulin was found to be
statistically significant higher in DAT-positive infants. </span> </p> <p> </p> <p> </p> <p class="MsoNoSpacingCxSpLast" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us">Conclusions: </span> </b> <span lang="en-us" style="font-size:10pt;font-family:’Arial Narrow’, sans-serif;" xml:lang="en-us"> Although LED
phototherapy is effective in DAT-positive patients, the need for  exchange transfusion and intravenöz
immunoglobulin  (IVIG) shows that there
is still a need for more effective phototherapy in these patients. </span> </p> <p> </p>}, number={2}, publisher={Harran Üniversitesi}