@article{article_531385, title={Retrospective analysis of risk factors for development of biliary fistula after liver cyst hydatid surgery}, journal={Archives of Clinical and Experimental Medicine}, volume={4}, pages={45–48}, year={2019}, DOI={10.25000/acem.531385}, author={Köse, Emin and Baz, Nilay Tuğba and Tazeoğlu, Deniz and Gürbüz, Mehmet Emin and Tok, Hasan and Özsoy, Ayhan and Karahan, Servet Rüştü}, keywords={Karaciğer kist hidatik hastalığı,safra fistülü,Echinococcus granulosus}, abstract={<p class="MsoNormal" style="line-height:200%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;" xml:lang="en-us">Aim: Hepatic hydatidosis is common parasitosis in Turkey and caused by Echinococcus granulosus. Biliary fistula is the most common complication after liver hydatid cyst surgery. The aim of this study was to investigate an appropriate treatment strategy for patients whose biliary fistula might develop, by revealing variables that affect biliary fistula. </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;" xml:lang="en-us">Methods: A total of 118 patients who underwent liver hydatid cyst surgery were included in this study. The following variables were analyzed between patients with biliary fistula (group 2) and without fistula (group 1): Age, gender, hematologic and liver function tests, and features of the cysts (type, cyst size, number, and localization). </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span lang="en-us" style="font-family:’Times New Roman’, serif;" xml:lang="en-us">Results: Cystobiliary fistula was detected in 19 (16%) of 118 patients. In-group 2, cyst size, </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;" xml:lang="en-us">white blood cell </span> <span lang="en-us" style="font-family:’Times New Roman’, serif;" xml:lang="en-us">, alkaline phosphatase and g-Glutamyl transpeptidase levels were higher than group 1 on univariate analysis (p=0.03, p=0.008, p=0.04 and p=0.001, respectively). In the multivariate model, only cyst diameter remained as an independent predictor (odds ratio 0.03, 95% confidence interval 0.002 to 0.06; p=0.03) On the receiver operating characteristic curve, the 100% sensitive, 100% specific, and optimal cutoffs of the cyst diameter were 7.5 cm, 4.0 cm and14.6 cm, respectively (The area under the receiver operator characteristic curve was 0.67). </span> </p> <p> </p> <p class="MsoNormal" style="line-height:200%;"> <span lang="en-us" style="font-size:12pt;font-family:’Times New Roman’, serif;" xml:lang="en-us">Conclusion: Preoperative cyst size is a valuable parameter for predicting biliary fistula. Our study suggests that cyst size greater than 7.5 cm is a risk factor for biliary fistula.  </span> <br /> </p>}, number={1}, publisher={Mustafa HASBAHÇECİ}