@article{article_547129, title={The Relationship Between Vitamin D and Ultrasonographic and Cytological Findings of Thyroid Nodules}, journal={Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi}, volume={52}, pages={206–213}, year={2019}, author={Atalay, Eray and Tur, Bilge Kağan and Kutas Kurt, Gülizar and Gürsoy, Gül}, keywords={Vitamin D,Tiroid Nodulü,Ultrasonografi,Sitoloji}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us">Objective: </span> </i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us"> There are reported associations between Vitamin D and some
cancers, but the relationship between vitamin D and thyroid cancers has not
been fully evaluated. The aim of this study was to evaluate the relationship
between vitamin D levels and ultrasonographical, cytological and postoperative
pathological data of the thyroid nodules. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us">Methods: </span> </i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us"> The study included 225 patients who underwent thyroidectomy
after thyroid fine needle aspiration biopsy (FNAB) due to the presence of
thyroid nodules.The preoperative ultrasonographical findings, the
cytopathological results obtained after FNAB and thyroidectomy operation and
serum vitamin D levels were recorded. The relationship between vitamin D levels
and ultrasonographical and cytological findings of thyroid nodules was
analyzed. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us">Results: </span> </i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us"> There was no statistically significant relationship between
vitamin D and ultrasonographical and histopathological results of thyroid
nodules. </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us">Conclusions: </span> </i> <span lang="en-us" style="font-size:12pt;line-height:150%;" xml:lang="en-us"> Our results showed that there were no relationship
between Vitamin D and ultrasonographical characteristics, biopsy and surgery
results of thyroid nodules. However, when we retrospectively examined our
results, we observed that very few cases with malignancy were found to be
benign in the preoperative FNAB evaluation. These patients had low vitamin D
levels and a nodule size of more than 2.5 cm. We think that more extensive
studies are needed to assess the association between malignancy and large
thyroid nodules associated with vitamin D deficiencies. </span> </p> <p> </p>}, number={3}, publisher={Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi}