@article{article_548331, title={Sotos Syndrome: A Case Report}, journal={Türkiye Çocuk Hastalıkları Dergisi}, volume={8}, pages={94–97}, year={2014}, author={Türkuçar, Serkan and Canpolat, Mehmet and Kaçar, Ayşe Bayram and Gümüş, Hakan and Per, Hüseyin and Kumandaş, Sefer}, keywords={Çocuk, Sotos sendromu, Uzun boy}, abstract={Tall Stature means that the person’s height percentile is above +2.5 standard deviation. It is commonly seen with endocrine problems. If it is accompanied with dysmorphic problems, the differential diagnosis includes metabolic disorders such as Marfan’s syndrome, homocystinuria, Beckwith–Wiedemann syndrome, neurofibromatosis, Weaver’s syndrome, Proteus and Proteus-like syndromes, fragile X syndrome and Sotos’ syndrome. In addition to increased height, Sotos syndrome patients may also have macrocephaly, excessive and disproportionate growth of the hands and feet, and a dysmorphic facial appearance. Congenital heart defects, mental retardation and behavioral problems may also be present. Our patient’s fetal measurements were 3 week ahead of normal fetal measurements in the antenatal period, and the height, weight and head circumference percentiles were greater than the 97th percentiles. The patient underwent surgery for a congenital cardiac disease (ASD and PDA). Hypertelorism, telecanthus,frontal bossing, arched nose and over-sized hands and feet were found by physical examination. Psychometric evaluation during the follow-up showed that the patient’s intelligence was below the normal range for his age group. Genetic analysis was performed due to possibility of Sotos’ syndrome. The patient was diagnosed as Sotos’ Syndrome due to mutations of Nuclear receptor binding SET-Domain 1 (NSD-1). We reported a patient who was diagnosed as Sotos’ syndrome and who is being treated for increased height in this article}, number={2}, publisher={T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}