TY - JOUR TT - Cell Adhesion Molecule: Nectin AU - Akkuş, Derya AU - Sönmez, Mehmet Fatih PY - 2012 DA - December JF - Sağlık Bilimleri Dergisi JO - JHS PB - Erciyes Üniversitesi WT - DergiPark SN - 1018-3655 SP - 205 EP - 211 VL - 21 IS - 3 KW - Bağlantı kompleksleri KW - hücre adezyon molekülleri KW - nektin N2 - molecules, which interact with each other or the extracellular fluid molecules, cell-cell and cellextracellular matrix protein molecules that provide their connection. Cell adhesion molecules play a role in the regulation of many events such as cell activation, migration, proliferation, differentiation and immunoglobulin-like cell adhesion molecules which comprise a family of four members, nectin-1, nectin-2, nectin-3, and nectin-4. Nectins contribute to the formation of a variety of cell–cell junctions, acting cooperatively with or independently of cadherins and these cause cell-cell adhesionhomophilically and heterophilically trans-interact. 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