TY - JOUR TT - The Effects of Treatment With Total Parenteral Lipid Emultion in Sheep Experimentally Induced Starvation Ketosis AU - Şıklaroglu, Reyda Kıyıcı AU - Güneş, Vehbi PY - 2017 DA - July JF - Sağlık Bilimleri Dergisi JO - JHS PB - Erciyes Üniversitesi WT - DergiPark SN - 1018-3655 SP - 126 EP - 132 VL - 26 IS - 2 KW - Ketozis KW - Koyun KW - Yağ emülsiyonu N2 - In this study, the effects of Total Parenteral Lipid Emulsions (TPLE) and 30% Dekstroz was compared to treatment of experimentally induced starvation ketosis in sheep. Eighteen nonpregnant, nonlactating sheep were randomly divided into 3 different study groups each containing six sheep. Subcutan phloryzin (100 mg/ kg) was injected together with feed restriction (1/4 of total ration) to induce the ketosis and lipid mobilisation. After clinical symptoms for ketosis in all groups, for control 0,9% NaCl in first group, 30% Dekstroz in second group IV and 20% TPLE in third group IV were administered to the each sheep in groups. Mean NEFA levels was a tendency to decrease after dextrose administration in group administered dextrose. In TPLE group, mean NEFA levels were not siginificantly higher after TPLE administraion (p=0.05). Mean triglyceride and glucose levels in sheep given TPLE were significantly higher than those of other groups. Clinical signs was recovered after in group given TPLE only. In conclusion, although 30% dextroz treatment was the most effective in decreasing of NEFA level, 20% TPLE inhibited clinical signs of starvation ketozis in sheep by providing urgent energy demand with increase of trigliserid and glucose levels. For this reason, TPLE was evaluated to be effective in correcting the clinical symptoms of fasting ketosis. CR - 1. Bergman EN. 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